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FLASH GENE

Symbol

PNPLA5

contributors: mct/npt - updated : 12-03-2009

HGNC name	patatin-like phospholipase domain containing 5
HGNC id	24888

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	22q13.31      Physical location : 44.275.558 - 44.287.893
Synonym name	GS2-like protein
Synonym symbol(s)	dJ388M5.4, GS2L, 4833426H19Rik
EC.number	3.1.1.-

DNA

TYPE	functioning gene
STRUCTURE	12.30 kb     9 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed PNPLA5 9 - 2581 48 429 - Kienesberger (2008)

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain         Skin/Tegument skin

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		acid
STRUCTURE

motifs/domains	a patatin-like domain
	two glycosaminoglycan sites

HOMOLOGY

Homologene

FAMILY

patatin-like phospholipase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION

implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson 2006)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

lipid/lipoprotein

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS