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Symbol GARIN5A contributors: mct - updated : 12-07-2022
HGNC name golgi associated RAB2 interactor 5A
HGNC id 25107
Location 19q13.33      Physical location : -
Synonym name
  • hypothetical protein LOC112703
  • family with sequence similarity 71, member E1
  • GARI like 5
    • Synonym symbol(s) FLJ43757, FLJ27522, FAM71E1, GARIL5
    DNA
    TYPE functioning gene
    STRUCTURE 10.06 kb     5 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1327 25 231 - 2017 28930687
    5 - 1375 - 247 - 2017 28930687
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
  • FAM71 family
    • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • GTP-binding activity of RAB2B is required for its localization on the Golgi apparatus and for recruitment of GARIN5A
  • RAB2B-GARIN5A complex promotes IFN responses against DNA viruses by regulating the cGAS-STING signaling axis
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS