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FLASH GENE
Symbol SERPINB10 contributors: - updated : 18-07-2006
HGNC name serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10
HGNC id 8942
Location 18q21.3      Physical location : 61.582.744 - 61.602.474
Genatlas name bomapin
Synonym name protease inhibitor 10 (ovalbumin type, bomapin)
Synonym symbol(s) PI10
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 19.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
text structure serpin cluster
MAPPING cloned Y linked N status provisional
Map see SPI@2 ,SERPINB8
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
high molecular weight serpin inhibitor
HOMOLOGY
Homologene
FAMILY serpin family,ovalbumin subgroup
CATEGORY enzyme , regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • may play a role in the regulation of protease activities during hematopoiesis
  • inhibiting tumor necrosis factor alpha -induced cell death
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS