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FLASH GENE

Symbol

ASB13

contributors: npt/ - updated : 19-09-2006

HGNC name	ankyrin repeat and SOCS box-containing 13
HGNC id	19765

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	10p15.1      Physical location : 5.680.819 - 5.708.558
Synonym symbol(s)	FLJ13134, MGC19879, ASB-13

DNA

TYPE	functioning gene
STRUCTURE	27.71 kb     6 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ASB13 6 - 2764 29.8 278 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic spleen         Digestive liver         Nervous brain         Reproductive female system uterus       Respiratory lung         Urinary kidney

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal     Nervous central

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	six N terminal ankyrin (ANK) repeats
	a conserved C-terminal SOCS box motif

HOMOLOGY

Homologene

FAMILY

ankyrin repeat and SOCS box-containing (ASB) family of proteins

CATEGORY

regulatory , signaling

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic

CELLULAR PROCESS	protein, post translation, targeting
	protein, degradation
	protein, ubiquitin dependent proteolysis

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

signal transduction

intracellular signaling cascade

a component

INTERACTION

DNA

RNA

small molecule

protein	JAK kinases
	activated cytokine receptors
	elonguin B/C complex

cell & other

REGULATION

induced by

cytokines

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS