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FLASH GENE
Symbol CDC42SE2 contributors: - updated : 29-03-2006
HGNC name CDC42 small effector 2
HGNC id 18547
Location 5q31      Physical location : 130.599.701 - 130.730.380
Synonym name
  • non-kinase CDC42 effector protein
  • Synonym symbol(s) LOC56990, SPEC2, FLJ21967
    DNA
    TYPE functioning gene
    STRUCTURE 31.00 kb     3 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticspleen   highly
    digestivemouthgingiva   
    Nervousbrain   highly
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • conserved N terminal region
  • one CRIB domain
  • HOMOLOGY
    Homologene
    FAMILY SPEC family
    CATEGORY chaperone/stress , structural protein
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION maybe acting as a scaffold to coordinate and/or mediate CDC42 regulation of kinase signaling and cell shape changes
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS