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FLASH GENE
Symbol CCNT2 contributors: mlc/npt - updated : 12-01-2008
HGNC name cyclin T2
HGNC id 1600
Location 2q21.3      Physical location : 135.676.392 - 135.714.584
Synonym name
  • SDS-stable vimentin-bound DNA fragment HEF42VIM22
  • cyclin T2a
  • cyclin T2b
  • subunit of positive elongation transcription factor b
    • Synonym symbol(s) CCT2, FLJ90560, MGC134840
    DNA
    TYPE functioning gene
    STRUCTURE 38.00 kb     10 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    9 - 4614 81 730 - Peng, Fu (2007)
    10 - 4513 - 663 - Peng, Fu (2007)
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx   highly
    Lymphoid/Immunelymph node   highly
    Respiratoryrespiratory tracttrachea  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Ccnt2
    Homologene
    FAMILY
  • cyclin family
  • cyclin C subfamily
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • plays a role in muscle differentiation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • CDK9 (to form P-TEFB)
  • interacting with PKN1 (partner in muscle differentiation)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene for nemaline myopathy 2
    Marker
    Therapy target
    ANIMAL & CELL MODELS