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FLASH GENE
Symbol DNAJC9 contributors: - updated : 12-05-2007
HGNC name DnaJ (Hsp40) homolog, subfamily C, member 9
HGNC id 19123
Location 10q22.3      Physical location : 75.002.583 - 75.007.025
Synonym name
  • DnaJ protein SB73
  • likely ortholog of rat J domain of DnaJ-like protein 1
  • human DnaJ/subfamily C/member 9
  • Synonym symbol(s) JDD1, SB73, HDJC9
    DNA
    TYPE functioning gene
    SPECIAL FEATURE head to head
    STRUCTURE 4.00 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
     liver    
    Hearing/Equilibriumearinnercochlea highly
    Nervousbrain    
    Respiratorylung    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    Text several tissues
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a typical N-terminal J domain
  • a zinc finger region
  • HOMOLOGY
    interspecies ortholog to rattus DNAJ-like protein
    Homologene
    FAMILY
    CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,nucleus
    basic FUNCTION universal cochaperone of HSP70/HSC73 proteins under both normal culture conditions and possibly heat shock stress conditions through the J domain
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to HSP70
  • interaction with HSC73/HSP70 (typical cofactor for HSP70/HSC73)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS