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FLASH GENE
Symbol STK16 contributors: npt/ - updated : 29-09-2007
HGNC name serine/threonine kinase 16
HGNC id 11394
Location 2q34-q37      Physical location : 220.110.191 - 220.115.059
Synonym name
  • protein kinase expressed in day 12 fetal liver
  • myristoylated and palmitoylated serine-threonine kinase
  • TGF-beta stimulated factor 1
  • protein kinase PKL12
    • Synonym symbol(s) KRCT, MPSK, TSF1, PKL12, FLJ39635, MPSK1,
    EC.number 2.7.1.37, 2.7.11.1
    DNA
    TYPE functioning gene
    STRUCTURE 3.44 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    text Variants 1 and 2 encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1682 34.6 305 - -
    - - 1440 34.6 305 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • myristylation and palmitylation sites in N terminus
  • C terminal protein kinase domain
    • HOMOLOGY
    interspecies homolog to murine Stk16
    Homologene
    FAMILY
  • serine/threonine kinase family
    • CATEGORY enzyme , transcription factor , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    intracellular,nucleus
    text localized with Golgi and Golgi-derived vesicles
    basic FUNCTION
  • autophosphocylation
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS exocytosis transport
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA binding to TGF-beta responsive CNP promoter and vascular endothelial growth factor gene promoter
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by TGF-beta
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS