Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PRKCH

contributors: mct - updated : 15-03-2011

HGNC name	protein kinase C, eta
HGNC id	9403

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in hepatocellular carcinoma, and may represent a molecular lesion in the development of more aggressive form

Susceptibility

to cerebral lacunar infarction to rheumatoid arthritis

Variant & Polymorphism SNP	-rs3783799 and rs2230500 increasing the risk of cerebral silent lacunar infarction
	could be associated with the patho-physiologic mechanism of rheumatoid arthritis

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     could represent a target for intervention aimed to reduce resistance to anti-cancer treatments

ANIMAL & CELL MODELS