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FLASH GENE

Symbol

RASGRF1

contributors: mct/pgu - updated : 25-10-2016

HGNC name	Ras protein-specific guanine nucleotide-releasing factor 1
HGNC id	9875

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in temporal lobe epilepsy (TLE)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     new potential therapeutic target to inhibit alveolar rhabdomyosarcomas growth

ANIMAL & CELL MODELS

	Rasgrf1 expression from the wild-type paternal allele contributes to learning and memory in neonatal mice
	Rasgrf1-deficient mice were significantly resistant to the development of dyskinesia during chronic L-dopa treatment