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FLASH GENE
Symbol RASGRF1 contributors: mct/pgu - updated : 25-10-2016
HGNC name Ras protein-specific guanine nucleotide-releasing factor 1
HGNC id 9875
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
in temporal lobe epilepsy (TLE)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
new potential therapeutic target to inhibit alveolar rhabdomyosarcomas growth
ANIMAL & CELL MODELS
  • Rasgrf1 expression from the wild-type paternal allele contributes to learning and memory in neonatal mice
  • Rasgrf1-deficient mice were significantly resistant to the development of dyskinesia during chronic L-dopa treatment