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FLASH GENE
Symbol DDR2 contributors: mct/pgu - updated : 15-01-2019
HGNC name discoidin domain receptor tyrosine kinase 2
HGNC id 2731
ASSOCIATED DISORDERS
corresponding disease(s) SEMD5 , BPCVAO
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • is a powerful biomarker that can predict poor prognosis as well as peritoneal dissemination (PD)
  • Therapy target
    SystemTypeDisorderPubmed
    neurologyneurodegenerative 
    DDR1 and DDR2 inhibition is a potential target to clear neurotoxic proteins and reduce inflammation in neurodegeneration
    cancerdigestivecolon
    might be an effective therapeutic target for colorectal cancer
    osteoarticularboneostéoporosis
    DDR2 may be therapeutic for patients with osteoporosis
    cancerreproductivebreast
    may serve as an accessible therapeutic target for the treatment of breast cancer
    ANIMAL & CELL MODELS