| 1 | BPCVAO, DDR2
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| Recurrent, Activating Variants in the Receptor Tyrosine Kinase DDR2 Cause Warburg-Cinotti Syndrome.
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| Xu L, Jensen H, Johnston JJ, Di Maria E, Kloth K, Cristea I, Sapp JC, Darling TN, Huryn LA, Tranebjærg L, Cinotti E, Kubisch C, Rødahl E, Bruland O, Biesecker LG, Houge G, Bredrup C.
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| Am J Hum Genet 103(6):976-983. doi: 10.1016/j.ajhg.2018.10.013. Epub 2018 Nov 15.
2018
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| 2 | DDR1, DDR2
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| Clustering, Spatial Distribution, and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen I.
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| Yeung DA, Shanker N, Sohail A, Weiss BA, Wang C, Wellmerling J, Das S, Ganju RK, Miller JLC, Herr AB, Fridman R, Agarwal G.
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| J Mol Biol Mol Biol. 2018 Nov 17. pii: S0022-2836(18)31238-5. doi: 10.1016/j.jmb.2018.11.015. [Epub ahead of print]
2018
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| 3 | BPCVAO, DDR2
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| Recurrent, Activating Variants in the Receptor Tyrosine Kinase DDR2 Cause Warburg-Cinotti Syndrome.
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| Xu L, Jensen H, Johnston JJ, Di Maria E, Kloth K, Cristea I, Sapp JC, Darling TN, Huryn LA, Tranebjærg L, Cinotti E, Kubisch C, Rødahl E, Bruland O, Biesecker LG, Houge G, Bredrup C.
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| Am J Hum Genet 103(6):976-983. doi: 10.1016/j.ajhg.2018.10.013. Epub 2018 Nov 15.
2018
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| 4 | DDR1, DDR2
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| DDR1 and DDR2 in skin.
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| Cario M.
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| Cell Adh Migr 12(4):386-393. doi: 10.1080/19336918.2018.1485618. Epub 2018 Aug 1.
2018
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| 5 | DDR2, SHC1
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| Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity.
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| Luczynski MT, Harrison PT, Lima N, Krasny L, Paul A, Huang PH.
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| Biochem Biophys Res Commun 501(1):124-130. doi: 10.1016/j.bbrc.2018.04.191. Epub 2018 May 3. Erratum in: Biochem Biophys Res Commun. 2018 Sep 26;504(1):360 2018
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| 6 | DDR1, DDR2
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| Discoidin domain receptor inhibition reduces neuropathology and attenuates inflammation in neurodegeneration models.
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| Hebron M, Peyton M, Liu X, Gao X, Wang R, Lonskaya I, Moussa CE.
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| J Neuroimmunol 311:1-9. doi: 10.1016/j.jneuroim.2017.07.009. Epub 2017 Aug 12.
2017
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| 7 | DDR2
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| DDR2 Expression Is Associated with a High Frequency of Peritoneal Dissemination and Poor Prognosis in Colorectal Cancer.
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| Sasaki S, Ueda M, Iguchi T, Kaneko M, Nakayama H, Watanabe T, Sakamoto A, Mimori K.
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| Anticancer Res 37(5):2587-2591.
2017
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| 8 | DDR2
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| Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts.
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| Majkowska I, Shitomi Y, Ito N, Gray NS, Itoh Y.
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| J Biol Chem 292(16):6633-6643. doi: 10.1074/jbc.M116.770057. Epub 2017 Mar 7.
2017
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| 9 | DDR2
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| Discoidin Receptor 2 Controls Bone Formation and Marrow Adipogenesis.
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| Ge C, Wang Z, Zhao G, Li B, Liao J, Sun H, Franceschi RT.
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| J Bone Miner Res 31(12):2193-2203. doi: 10.1002/jbmr.2893. Epub 2016 Oct 31. Erratum in: J Bone Miner Res. 2018 Nov;33(11):2081.
2016
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| 10 | DDR2
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| DDR2 (discoidin domain receptor 2) suppresses osteoclastogenesis and is a potential therapeutic target in osteoporosis.
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| Zhang Y, Su J, Wu S, Teng Y, Yin Z, Guo Y, Li J, Li K, Yao L, Li X.
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| Sci Signal 8(369):ra31. doi: 10.1126/scisignal.2005835.
2015
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| 11 | CBLB, DDR2
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| Ubiquitin ligase Cbl-b acts as a negative regulator in discoidin domain receptor 2 signaling via modulation of its stability.
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| Yu J, Zhao H, Zhang Y, Liu YC, Yao L, Li X, Su J.
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| FEBS Lett 588(9):1509-14. doi: 10.1016/j.febslet.2014.03.003. Epub 2014 Mar 12.
2014
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| 12 | DDR2
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| Discoidin domain receptor 2 (DDR2) promotes breast cancer cell metastasis and the mechanism implicates epithelial-mesenchymal transition programme under hypoxia.
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| Ren T, Zhang W, Liu X, Zhao H, Zhang J, Zhang J, Li X, Zhang Y, Bu X, Shi M, Yao L, Su J.
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| J Pathol 234(4):526-37. doi: 10.1002/path.4415. Epub 2014 Sep 15.
2014
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| 13 | DDR2, IL12A
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| Induction of IL-12 production by the activation of discoidin domain receptor 2 via NF-κB and JNK pathway.
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| Poudel B, Ki HH, Lee YM, Kim DK.
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| Biochem Biophys Res Commun 434(3):584-8. doi: 10.1016/j.bbrc.2013.03.118. Epub 2013 Apr 10. 2013
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| 14 | DDR2
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| DDR2 plays a role in fibroblast migration independent of adhesion ligand and collagen activated DDR2 tyrosine kinase.
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| Herrera-Herrera ML, Quezada-Calvillo R.
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| Biochem Biophys Res Commun 429(1-2):39-44. doi: 10.1016/j.bbrc.2012.10.103. Epub 2012 Nov 3.
2012
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| 15 | DDR2
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| Discoidin domain receptor 2 is a critical regulator of epithelial-mesenchymal transition.
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| Walsh LA, Nawshad A, Medici D.
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| Matrix Biol 30(4):243-7. doi: 10.1016/j.matbio.2011.03.007. Epub 2011 Apr 6.
2011
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| 16 | DDR2, SEMD5
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| Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients.
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| Ali BR, Xu H, Akawi NA, John A, Karuvantevida NS, Langer R, Al-Gazali L, Leitinger B.
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| Hum Mol Genet 19(11):2239-50. Epub 2010 Mar 10.PMID: 20223752 2010
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| 17 | DDR2, SEMD5
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| Mutations in DDR2 gene cause SMED with short limbs and abnormal calcifications.
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| Bargal R, Cormier-Daire V, Ben-Neriah Z, Le Merrer M, Sosna J, Melki J, Zangen DH, Smithson SF, Borochowitz Z, Belostotsky R, Raas-Rothschild A.
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| Am J Hum Genet 84(1):80-4. Epub 2008 Dec 24.
2009
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| 18 | COL10A1, DDR2
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| The discoidin domain receptor DDR2 is a receptor for type X collagen.
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| Leitinger B, Kwan AP.
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| Matrix Biol 25(6):355-64. Epub 2006 May 26. 2006
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| 19 | DDR1, DDR2
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| The discoidin domain receptor tyrosine kinases are activated by collagen.
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| Vogel W, et al.
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| Mol Cell 1 : 13-23. 1997
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| 20 | DDR2
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| Structure, expression and chromosomal mapping of TKT from man and mouse : a new subclass of receptor tyrosine kinases with a factor VIII-like domain.
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| Karn T, et al.
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| Oncogene 8 : 3433-3440. 1993
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| 21 | DDR2, PTK3B, FRK, PTK6, PTK7, MST1R, RYKP
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| A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.
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| Lee ST, et al.
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| Oncogene 8 : 3403-3410. 1993
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