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FLASH GENE

Symbol

FOSL1

contributors: mct/npt/shn - updated : 04-12-2012

HGNC name	FOS-like antigen 1
HGNC id	13718

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Ectopic expression of the transcription factor Fra-1 in transgenic mice leads to osteosclerosis
	fra-1-knockout mice die in utero likely due to placental defects
	Mice lacking Fra-1 (fra-1(delta/delta)) are viable and develop osteopenia, a low bone mass disease