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FLASH GENE

Symbol

LIMD1

contributors: mct/npt/pgu - updated : 04-01-2010

HGNC name	LIM domains containing 1
HGNC id	6612

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in lung cancer, by CpG methylation constitutional     --over   during osteoclast differentiation tumoral     --low   in lung and breast cancers (absence/loss of nuclear staining showed a strong correlation with patient survival and was indicative of poor prognosis)

Susceptibility

to breast cancer

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS