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FLASH GENE

Symbol

APPL1

contributors: mct/pgu - updated : 17-05-2017

HGNC name	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
HGNC id	24035

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Appl1 Tg mice exhibit improved peripheral metabolism, reduced cardiac lipotoxicity, and improved insulin sensitivity
	Appl1 knockout mice exhibit glucose intolerance and impaired glucose-stimulated insulin secretion (GSIS)