Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

EXOC6B

contributors: mct - updated : 03-05-2014

HGNC name	exocyst complex component 6B
HGNC id	17085

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine neuroendocrine pituitary     moderately Nervous brain           nerve       moderately Reproductive female system placenta     predominantly Respiratory respiratory tract larynx     highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Nervous peripherous

cells

System Cell Pubmed Species Stage Rna symbol Nervous neuron

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	homolog to rattus Rsec15
	homolog to murine Exoc6b (99.1 pc)

Homologene

FAMILY

SEC15 family

CATEGORY

signaling

SUBCELLULAR LOCALIZATION	plasma membrane
text	docking vesicles to the plasma membrane

basic FUNCTION	involved in the docking of exocystic vesicles with fusion sites on the plasma membrane
	acting as a regulator of polarized secretion
	is a gene relevant for intellectual development and electrophysiological stability

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

exocytosis transport

text	protein transport

PATHWAY

metabolism

signaling

signal transduction

a component

component of brain exocyst complex, composed of SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70 and EXO84

INTERACTION

DNA

RNA

small molecule

protein

RALA binding

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS