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FLASH GENE
Symbol EXOC6B contributors: mct - updated : 03-05-2014
HGNC name exocyst complex component 6B
HGNC id 17085
DNA
TYPE functioning gene
STRUCTURE 650.06 kb     22 Exon(s)
MAPPING cloned Y linked N status confirmed
regionally located in the PARK3 region
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
22 - 2594 94 811 - 2008 18424204
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineneuroendocrinepituitary  moderately
Nervousbrain    
 nerve   moderately
Reproductivefemale systemplacenta  predominantly
Respiratoryrespiratory tractlarynx  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to rattus Rsec15
homolog to murine Exoc6b (99.1 pc)
Homologene
FAMILY
  • SEC15 family
  • CATEGORY signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    text docking vesicles to the plasma membrane
    basic FUNCTION
  • involved in the docking of exocystic vesicles with fusion sites on the plasma membrane
  • acting as a regulator of polarized secretion
  • is a gene relevant for intellectual development and electrophysiological stability
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS exocytosis transport
    text
  • protein transport
  • PATHWAY
    metabolism
    signaling signal transduction
    a component
  • component of brain exocyst complex, composed of SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70 and EXO84
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • RALA binding
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS