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FLASH GENE
Symbol FUT6 contributors: mct - updated : 11-06-2020
HGNC name fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
HGNC id 4017
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --other  
altered expression of fucosylation pathway gene(FUT6), correlated with poor survival in patients with non&8209;small cell lung cancer (NSCLC)
Susceptibility to intestinal-type gastric cancer
Variant & Polymorphism other
  • variants (and haplotypes) in FUT2 (Se), FUT3 (Le) and FUT6 associated with intestinal-type gastric cancer
  • Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerreproductiveprostate
    may serve as a viable drug target in preclinical tests of therapeutics for reduction of PCa bone metastasis
    ANIMAL & CELL MODELS