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FLASH GENE

Symbol

CASP9

contributors: mct/npt/pgu - updated : 18-05-2014

HGNC name	caspase 9, apoptosis-related cysteine peptidase
HGNC id	1511

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       gain of function in neurons of Alzheimer disease (before cleavage of tau and formation of neurofibrillary tangles)

Susceptibility

to modification of survival in non-small-cell lung cancer (NSCLC)

Variant & Polymorphism other	rs4645981 polymorphisms may affect survival in early-stage NSCLC

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS