Citations for
1ATG7, CASP9
A Complex between Atg7 and Caspase-9: A NOVEL MECHANISM OF CROSS-REGULATION BETWEEN AUTOPHAGY AND APOPTOSIS.
Han J, Hou W, Goldstein LA, Stolz DB, Watkins SC, Rabinowich H.
J Biol Chem 289(10):6485-97. doi: 10.1074/jbc.M113.536854. Epub 2013 Dec 20. 2014
2CASP3, CASP9, MAPK14, ROBO2, SLIT1
Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization.
Campbell DS, Okamoto H.
J Cell Biol 203(4):657-72. doi: 10.1083/jcb.201303072. 2013
3CASP3, CASP7, CASP9
Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis.
Brentnall M, Rodriguez-Menocal L, De Guevara RL, Cepero E, Boise LH.
BMC Cell Biol 14:32. doi: 10.1186/1471-2121-14-32. 2013
4CASP3, CASP9
The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3.
Yuan S, Yu X, Asara JM, Heuser JE, Ludtke SJ, Akey CW.
Structure 19(8):1084-96. 2011
5CASP9
Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.
Manns J, Daubrawa M, Driessen S, Paasch F, Hoffmann N, Löffler A, Lauber K, Dieterle A, Alers S, Iftner T, Schulze-Osthoff K, Stork B, Wesselborg S.
FASEB J 25(9):3250-61. Epub 2011 Jun 9. 2011
6CASP9
Essential role for p53 and caspase-9 in DNA damaging drug-induced apoptosis in neuroblastoma IMR32 cells.
Li T, Cui ZB, Ke XX, Tan J, Li FF, Li T, Wang XW, Cui HJ.
DNA Cell Biol 30(12):1045-50. Epub 2011 May 25. 2011
7CASP9, PDCD6, PDCD6IP, SHISA5
Alix is involved in caspase 9 activation during calcium-induced apoptosis.
Strappazzon F, Torch S, Chatellard-Causse C, Petiot A, Thibert C, Blot B, Verna JM, Sadoul R.
Biochem Biophys Res Commun 397(1):64-9. Epub 2010 May 21.PMID: 20471954 2010
8BIRC2, CASP9
cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome.
Burke SP, Smith L, Smith JB.
J Biol Chem 285(39):30061-8. Epub 2010 Jul 28. 2010
9CASP9
Caspase-9-dependent nuclear translocation of cytochrome c in hypoxic injury.
Kim JY, Kim YJ, Seok KO, Lee S, Park JH.
Pathobiology 77(6):320-7. Epub 2011 Jan 24. 2010
10CASP9
Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a.
Shultz JC, Goehe RW, Wijesinghe DS, Murudkar C, Hawkins AJ, Shay JW, Minna JD, Chalfant CE.
Cancer Res 70(22):9185-96. Epub 2010 Nov 2. 2010
11CASP1, CASP10, CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9
Mutational analysis of CASP1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 14 genes in gastrointestinal stromal tumors.
Kim YR, Kim KM, Yoo NJ, Lee SH.
Hum Pathol 40(6):868-71. Epub 2009 Mar 9. 2009
12APAF1, CASP9
Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1.
Zuo Y, Xiang B, Yang J, Sun X, Wang Y, Cang H, Yi J.
Cell Res 19(4):449-57. 2009
13CASP9
Polymorphisms in the CASPASE genes and survival in patients with early-stage non-small-cell lung cancer.
Yoo SS, Choi JE, Lee WK, Choi YY, Kam S, Kim MJ, Jeon HS, Lee EB, Kim DS, Lee MH, Kim IS, Jheon S, Park JY.
J Clin Oncol 27(34):5823-9. Epub 2009 Oct 13. 2009
14CASP9
Caspase polymorphisms and genetic susceptibility to multiple myeloma.
Hosgood HD 3rd, Baris D, Zhang Y, Zhu Y, Zheng T, Yeager M, Welch R, Zahm S, Chanock S, Rothman N, Lan Q.
Hematol Oncol ematol Oncol. 2008 Apr 1. [Epub ahead of print] 2008
15CASP9, DYRK1A
The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.
Laguna A, Aranda S, Barallobre MJ, Barhoum R, Fernández E, Fotaki V, Delabar JM, de la Luna S, de la Villa P, Arbonés ML.
Dev Cell 15(6):841-53. 2008
16RNF2, CASP3, CASP9
Polycomb group protein RING1B is a direct substrate of Caspases-3 and -9.
Wong CK, Chen Z, So KL, Li D, Li P.
Biochim Biophys Acta 1773(6):844-52. Epub 2007 Feb 22. 2007
17CASP3, CASP9, XIAP
Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9.
Denault JB, Eckelman BP, Shin H, Pop C, Salvesen GS.
Biochem J 405(1):11-9. 2007
18CASP9, HAX1
Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition.
Han Y, Chen YS, Liu Z, Bodyak N, Rigor D, Bisping E, Pu WT, Kang PM.
Circ Res 99(4):415-23. Epub 2006 Jul 20. 2006
19CASP9, DIABLO, XIAP
X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO.
Morizane Y, Honda R, Fukami K, Yasuda H.
J Biochem (Tokyo) 137(2):125-32. 2005
20APAF1, CASP9, APIP
Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein.
Cho DH, Hong YM, Lee HJ, Woo HN, Pyo JO, Mak TW, Jung YK.
J Biol Chem 279(38):39942-50. Epub 2004 Jul 15. 2004
21CASP9, DFFA
Analyses of apoptotic regulators CASP9 and DFFA at 1P36.2, reveal rare allele variants in human neuroblastoma tumours.
Abel F, Sjoberg RM, Ejeskar K, Krona C, Martinsson T.
Br J Cancer 86(4):596-604. 2002
22CASP9
Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain.
Rohn TT, Rissman RA, Davis MC, Kim YE, Cotman CW, Head E.
Neurobiol Dis 11(2):341-54. 2002
23CASP9, APAF1
Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.
Teitz T, Wei T, Liu D, Valentine V, Valentine M, Grenet J, Lahti JM, Kidd VJ.
Oncogene 21(12):1848-58. 2002
24CASP9, DIABLO, XIAP
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee RA, Robbins PD, Fernandes-Alnemri T, Shi Y, Alnemri ES.
Nature 410(6824):112-6. 2001
25BCL2, CASP9, DIABLO
Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2.
Adrain C, Creagh EM, Martin SJ.
EMBO J 20(23):6627-36. 2001
26CASP9, CFLAR
Genomic organization of the human caspase-9 gene on Chromosome 1p36. 1-p36.3.
Hadano S, et al.
Mamm Genome 10(7):757-60. No abstract available 1999
27APAF1, CASP9
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation.
Saleh A, et al.
J Biol Chem 274(25):17941-5 1999
28APAF1, CASP9
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.
Hu Y, et al.
EMBO J 18(13):3586-95 1999
29APAF1, CASP9
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9.
Zou H, Li Y, Liu X, Wang X.
J Biol Chem 274(17):11549-56. 1999
30APAF1, CASP9
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization.
Srinivasula SM, et al.
Mol Cell 1(7):949-57 1998
31CASP9
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
Li P, et al.
Cell 91(4):479-89 1997