| 1 | ATG7, CASP9
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| A Complex between Atg7 and Caspase-9: A NOVEL MECHANISM OF CROSS-REGULATION BETWEEN AUTOPHAGY AND APOPTOSIS.
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| Han J, Hou W, Goldstein LA, Stolz DB, Watkins SC, Rabinowich H.
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| J Biol Chem 289(10):6485-97. doi: 10.1074/jbc.M113.536854. Epub 2013 Dec 20.
2014
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| 2 | CASP3, CASP9, MAPK14, ROBO2, SLIT1
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| Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization.
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| Campbell DS, Okamoto H.
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| J Cell Biol 203(4):657-72. doi: 10.1083/jcb.201303072.
2013
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| 3 | CASP3, CASP7, CASP9
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| Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis.
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| Brentnall M, Rodriguez-Menocal L, De Guevara RL, Cepero E, Boise LH.
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| BMC Cell Biol 14:32. doi: 10.1186/1471-2121-14-32.
2013
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| 4 | CASP3, CASP9
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| The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3.
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| Yuan S, Yu X, Asara JM, Heuser JE, Ludtke SJ, Akey CW.
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| Structure 19(8):1084-96.
2011
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| 5 | CASP9
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| Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.
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| Manns J, Daubrawa M, Driessen S, Paasch F, Hoffmann N, Löffler A, Lauber K, Dieterle A, Alers S, Iftner T, Schulze-Osthoff K, Stork B, Wesselborg S.
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| FASEB J 25(9):3250-61. Epub 2011 Jun 9.
2011
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| 6 | CASP9
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| Essential role for p53 and caspase-9 in DNA damaging drug-induced apoptosis in neuroblastoma IMR32 cells.
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| Li T, Cui ZB, Ke XX, Tan J, Li FF, Li T, Wang XW, Cui HJ.
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| DNA Cell Biol 30(12):1045-50. Epub 2011 May 25.
2011
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| 7 | CASP4, CASP9
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| Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells.
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| Yamamuro A, Kishino T, Ohshima Y, Yoshioka Y, Kimura T, Kasai A, Maeda S.
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| J Pharmacol Sci 115(2):239-43. Epub 2011 Jan 26.
2011
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| 8 | CASP9, PDCD6, PDCD6IP, SHISA5
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| Alix is involved in caspase 9 activation during calcium-induced apoptosis.
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| Strappazzon F, Torch S, Chatellard-Causse C, Petiot A, Thibert C, Blot B, Verna JM, Sadoul R.
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| Biochem Biophys Res Commun 397(1):64-9. Epub 2010 May 21.PMID: 20471954 2010
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| 9 | BIRC2, CASP9
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| cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome.
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| Burke SP, Smith L, Smith JB.
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| J Biol Chem 285(39):30061-8. Epub 2010 Jul 28.
2010
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| 10 | CASP9
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| Caspase-9-dependent nuclear translocation of cytochrome c in hypoxic injury.
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| Kim JY, Kim YJ, Seok KO, Lee S, Park JH.
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| Pathobiology 77(6):320-7. Epub 2011 Jan 24.
2010
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| 11 | CASP9
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| Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a.
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| Shultz JC, Goehe RW, Wijesinghe DS, Murudkar C, Hawkins AJ, Shay JW, Minna JD, Chalfant CE.
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| Cancer Res 70(22):9185-96. Epub 2010 Nov 2.
2010
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| 12 | CASP1, CASP10, CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9
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| Mutational analysis of CASP1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 14 genes in gastrointestinal stromal tumors.
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| Kim YR, Kim KM, Yoo NJ, Lee SH.
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| Hum Pathol 40(6):868-71. Epub 2009 Mar 9.
2009
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| 13 | APAF1, CASP9
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| Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1.
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| Zuo Y, Xiang B, Yang J, Sun X, Wang Y, Cang H, Yi J.
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| Cell Res 19(4):449-57.
2009
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| 14 | CASP9
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| Polymorphisms in the CASPASE genes and survival in patients with early-stage non-small-cell lung cancer.
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| Yoo SS, Choi JE, Lee WK, Choi YY, Kam S, Kim MJ, Jeon HS, Lee EB, Kim DS, Lee MH, Kim IS, Jheon S, Park JY.
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| J Clin Oncol 27(34):5823-9. Epub 2009 Oct 13.
2009
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| 15 | CASP9
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| Caspase polymorphisms and genetic susceptibility to multiple myeloma.
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| Hosgood HD 3rd, Baris D, Zhang Y, Zhu Y, Zheng T, Yeager M, Welch R, Zahm S, Chanock S, Rothman N, Lan Q.
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| Hematol Oncol ematol Oncol. 2008 Apr 1. [Epub ahead of print] 2008
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| 16 | CASP9, DYRK1A
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| The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.
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| Laguna A, Aranda S, Barallobre MJ, Barhoum R, Fernández E, Fotaki V, Delabar JM, de la Luna S, de la Villa P, Arbonés ML.
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| Dev Cell 15(6):841-53. 2008
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| 17 | RNF2, CASP3, CASP9
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| Polycomb group protein RING1B is a direct substrate of Caspases-3 and -9.
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| Wong CK, Chen Z, So KL, Li D, Li P.
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| Biochim Biophys Acta 1773(6):844-52. Epub 2007 Feb 22. 2007
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| 18 | CASP3, CASP9, XIAP
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| Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9.
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| Denault JB, Eckelman BP, Shin H, Pop C, Salvesen GS.
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| Biochem J 405(1):11-9.
2007
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| 19 | CASP9, HAX1
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| Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition.
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| Han Y, Chen YS, Liu Z, Bodyak N, Rigor D, Bisping E, Pu WT, Kang PM.
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| Circ Res 99(4):415-23. Epub 2006 Jul 20. 2006
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| 20 | CASP9, DIABLO, XIAP
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| X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO.
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| Morizane Y, Honda R, Fukami K, Yasuda H.
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| J Biochem (Tokyo) 137(2):125-32. 2005
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| 21 | APAF1, CASP9, APIP
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| Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein.
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| Cho DH, Hong YM, Lee HJ, Woo HN, Pyo JO, Mak TW, Jung YK.
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| J Biol Chem 279(38):39942-50. Epub 2004 Jul 15. 2004
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| 22 | CASP9, DFFA
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| Analyses of apoptotic regulators CASP9 and DFFA at 1P36.2, reveal rare allele variants in human neuroblastoma tumours.
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| Abel F, Sjoberg RM, Ejeskar K, Krona C, Martinsson T.
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| Br J Cancer 86(4):596-604. 2002
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| 23 | CASP9
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| Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain.
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| Rohn TT, Rissman RA, Davis MC, Kim YE, Cotman CW, Head E.
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| Neurobiol Dis 11(2):341-54. 2002
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| 24 | CASP9, APAF1
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| Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.
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| Teitz T, Wei T, Liu D, Valentine V, Valentine M, Grenet J, Lahti JM, Kidd VJ.
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| Oncogene 21(12):1848-58. 2002
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| 25 | CASP9, DIABLO, XIAP
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| A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
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| Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J, Lee RA, Robbins PD, Fernandes-Alnemri T, Shi Y, Alnemri ES.
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| Nature 410(6824):112-6. 2001
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| 26 | BCL2, CASP9, DIABLO
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| Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2.
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| Adrain C, Creagh EM, Martin SJ.
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| EMBO J 20(23):6627-36. 2001
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| 27 | CASP9, CFLAR
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| Genomic organization of the human caspase-9 gene on Chromosome 1p36. 1-p36.3.
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| Hadano S, et al.
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| Mamm Genome 10(7):757-60. No abstract available 1999
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| 28 | APAF1, CASP9
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| Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation.
|
| Saleh A, et al.
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| J Biol Chem 274(25):17941-5 1999
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| 29 | APAF1, CASP9
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| Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.
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| Hu Y, et al.
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| EMBO J 18(13):3586-95 1999
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| 30 | APAF1, CASP9
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| An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9.
|
| Zou H, Li Y, Liu X, Wang X.
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| J Biol Chem 274(17):11549-56. 1999
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| 31 | APAF1, CASP9
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| Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization.
|
| Srinivasula SM, et al.
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| Mol Cell 1(7):949-57 1998
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| 32 | CASP9
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| Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
|
| Li P, et al.
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| Cell 91(4):479-89 1997
|