Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --over
|  
|
in autoimmune disease |
constitutional
|  
|  
| --over
|  
|
in monocytes and T cells significantly higher in multiple sclerosis |
constitutional
|  
|  
| --over
|  
|
with TNF, TNFSF13B, TNFSF13 in Behcet disease |
constitutional
|  
|  
| --over
|  
|
in inflammatory skin lesions of psoriasis |
tumoral
|  
|  
| --over
|  
|
in skin squamous cell carcinomas |
tumoral
|  
|  
| --over
|  
|
correlates with poor prognosis in clear cell renal cell carcinoma |
tumoral
|  
|  
| --over
|  
|
in breast carcinoma tissue lesions |
constitutional
|  
|  
| --over
|  
|
in systemic lupus erythematosus (SLE) |
tumoral
|  
|  
| --over
|  
|
IRF8 and TNFSF13 expression was significantly higher in lymphomas with IGH rearrangements targeting these loci |