| basic FUNCTION
| cell cycle control, candidate for ovarian tumor suppression gene |
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involved in T-cell lymphomagenesis |
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function through interaction with other septins and small GTPase Rho-mediated signaling |
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dispensable for the early stages of cell division, but is critical for the final separation of daughter cells  |
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mediates the localization of the vesicle-tethering exocyst complex to the midbody, providing mechanistic insight into the role of SEPT9 during abscission |
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importance of SEPT9 for septin filament formation and general cell stability |
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guanosine triphosphatase-binding protein required for cytokinesis |
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assemble into rod-shaped oligomeric complexes that join end-on-end to form filaments |
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SEPT9 holds a terminal position in the septin octamers, mediating abscission-specific polymerization during cytokinesis |
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SEPT9 expression level directs the hexamer-to-octamer ratio, and the isoform composition and expression level together determine higher-order arrangements of septins |
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both SEPT9 and PIN1 are critical for mediating the final separation of daughter cells |
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plays multiple roles in abscission, one of which is regulated by the action of CDK1 and PIN1 |
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negatively regulates EGFR degradation by preventing the association of the ubiquitin ligase CBL with SH3KBP1, resulting in reduced EGFR ubiquitylation |
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modulates likely the interactions of KIF17 with membrane cargo |
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SEPTIN2, SEPTIN7, and SEPTIN9 are required for efficient bacterial invasion |
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SEPT9 promotes the formation and maintenance of long stable MTs through a mechanism that may involve recruitment of unpolymerized tubulin to the MT lattice |
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expressed and synthesized during differentiation of human osteoclasts |
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play a previously unappreciated role in osteoclastic bone resorption |
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SEPTIN9 regulates the recruitment of transition zone proteins on Golgi-derived vesicles by activating the exocyst via RhoA to allow the formation of primary cilia |
