| 1 | ARHGEF18, SEPTIN9
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| Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone. 2023 PMID:
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| Safavian D, Kim MS, Xie H, El-Zeiry M, Palander O, Dai L, Collins RF, Froese C, Shannon R, Nagata KI, Trimble WS.
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| J Cell Biol. Apr 3;222(4):e201911062. doi: 10.1083/jcb.201911062. Epub 2023 Mar 13. 2023
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| 2 | SEPTIN9
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| Septins are critical regulators of osteoclastic bone resorption.
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| Møller AMJ, Füchtbauer EM, Brüel A, Andersen TL, Borggaard XG, Pavlos NJ, Thomsen JS, Pedersen FS, Delaisse JM, Søe K.
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| Sci Rep 8(1):13016. doi: 10.1038/s41598-018-31159-1. 2018
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| 3 | SEPTIN9
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| Regulation of microtubule plus end dynamics by septin 9.
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| Nakos K, Rosenberg M, Spiliotis ET.
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| Cytoskeleton (Hoboken) ytoskeleton (Hoboken). 2018 Aug 24. doi: 10.1002/cm.21488. [Epub ahead of print] 2018
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| 4 | HNA, SEPTIN9
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| Hereditary neuralgic amyotrophy in childhood caused by duplication within the SEPT9 gene: A family study.
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| Neubauer K, Boeckelmann D, Koehler U, Kracht J, Kirschner J, Pendziwiat M, Zieger B.
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| Cytoskeleton (Hoboken) ytoskeleton (Hoboken). 2018 Jul 18. doi: 10.1002/cm.21479. [Epub ahead of print] 2018
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| 5 | SEPTIN2, SEPTIN9, sEPTIN7
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| Septin-regulated actin dynamics promote Salmonella invasion of host cells.
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| Boddy KC, Gao AD, Truong D, Kim MS, Froese CD, Trimble WS, Brumell JH.
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| Cell Microbiol 20(10):e12866. doi: 10.1111/cmi.12866. Epub 2018 Jul 26.
2018
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| 6 | SEPTIN9
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| Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis.
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| Wu Y, Bu F, Yu H, Li W, Huang C, Meng X, Zhang L, Ma T, Li J.
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| Toxicol Appl Pharmacol 315:35-49. doi: 10.1016/j.taap.2016.12.002. Epub 2016 Dec 6. 2017
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| 7 | KIF17, SEPTIN9
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| Septin 9 interacts with kinesin KIF17 and interferes with the mechanism of NMDA receptor cargo binding and transport.
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| Bai X, Karasmanis EP, Spiliotis ET.
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| Mol Biol Cell 27(6):897-906. doi: 10.1091/mbc.E15-07-0493. Epub 2016 Jan 28. 2016
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| 8 | SEPTIN9, SH3KBP1
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| SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR.
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| Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M.
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| J Cell Sci 128(2):397-407. doi: 10.1242/jcs.162206. 2015
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| 9 | SEPTIN9
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| Simultaneous Analysis of SEPT9 Promoter Methylation Status, Micronuclei Frequency, and Folate-Related Gene Polymorphisms: The Potential for a Novel Blood-Based Colorectal Cancer Biomarker.
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| Ravegnini G, Zolezzi Moraga JM, Maffei F, Musti M, Zenesini C, Simeon V, Sammarini G, Festi D, Hrelia P, Angelini S.
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| Int J Mol Sci 16(12):28486-97. doi: 10.3390/ijms161226113. 2015
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| 10 | SEPTIN9
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| High methylation of the SEPT9 gene in Chinese colorectal cancer patients.
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| Su XL, Wang YF, Li SJ, Zhang F, Cui HW.
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| Genet Mol Res 13(2):2513-20. doi: 10.4238/2014.January.17.5. 2014
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| 11 | MAP4, SEPTIN2, SEPTIN7, SEPTIN9
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| Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length.
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| Ghossoub R, Hu Q, Failler M, Rouyez MC, Spitzbarth B, Mostowy S, Wolfrum U, Saunier S, Cossart P, Jamesnelson W, Benmerah A.
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| J Cell Sci 126(Pt 12):2583-94. doi: 10.1242/jcs.111377. Epub 2013 Apr 9. 2013
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| 12 | CDK1, PIN1, PLK1, SEPTIN9
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| Mitotic regulation of SEPT9 protein by cyclin-dependent kinase 1 (Cdk1) and Pin1 protein is important for the completion of cytokinesis.
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| Estey MP, Di Ciano-Oliveira C, Froese CD, Fung KY, Steels JD, Litchfield DW, Trimble WS.
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| J Biol Chem 288(42):30075-86. doi: 10.1074/jbc.M113.474932. Epub 2013 Aug 29. 2013
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| 13 | HNA, SEPTIN9
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| Novel septin 9 repeat motifs altered in neuralgic amyotrophy bind and bundle microtubules.
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| Bai X, Bowen JR, Knox TK, Zhou K, Pendziwiat M, Kuhlenbäumer G, Sindelar CV, Spiliotis ET.
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| J Cell Biol 203(6):895-905. 2013
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| 14 | SEPTIN9
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| Expression of the SEPT9_i4 isoform confers resistance to microtubule-interacting drugs.
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| Chacko AD, McDade SS, Chanduloy S, Church SW, Kennedy R, Price J, Hall PA, Russell SE.
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| Cell Oncol (Dordr) 35(2):85-93. doi: 10.1007/s13402-011-0066-0. Epub 2012 Jan 26. 2012
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| 15 | SEPTIN9
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| Mammalian SEPT9 isoforms direct microtubule-dependent arrangements of septin core heteromers.
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| Sellin ME, Stenmark S, Gullberg M.
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| Mol Biol Cell 23(21):4242-55. doi: 10.1091/mbc.E12-06-0486. Epub 2012 Sep 5. 2012
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| 16 | SEPTIN9
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| SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent functions in abscission.
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| Kim MS, Froese CD, Estey MP, Trimble WS.
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| J Cell Biol 195(5):815-26. doi: 10.1083/jcb.201106131. 2011
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| 17 | SEPTIN9
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| Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression.
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| Connolly D, Yang Z, Castaldi M, Simmons N, Oktay MH, Coniglio S, Fazzari MJ, Verdier-Pinard P, Montagna C.
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| Breast Cancer Res 13(4):R76. doi: 10.1186/bcr2924. 2011
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| 18 | SEPTIN9
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| Septin9 is involved in septin filament formation and cellular stability.
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| Füchtbauer A, Lassen LB, Jensen AB, Howard J, Quiroga Ade S, Warming S, Sørensen AB, Pedersen FS, Füchtbauer EM.
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| Biol Chem 392(8-9):769-77. doi: 10.1515/BC.2011.088. 2011
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| 19 | SEPTIN9
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| The influence of methylated septin 9 gene on RNA and protein level in colorectal cancer.
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| Tóth K, Galamb O, Spisák S, Wichmann B, Sipos F, Valcz G, Leiszter K, Molnár B, Tulassay Z.
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| Pathol Oncol Res 17(3):503-9. doi: 10.1007/s12253-010-9338-7. Epub 2011 Jan 26. 2011
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| 20 | SEPTIN2, SEPTIN7, SEPTIN9
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| Characterization of human septin interactions.
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| Sandrock K, Bartsch I, Bläser S, Busse A, Busse E, Zieger B.
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| Biol Chem 392(8-9):751-61. doi: 10.1515/BC.2011.081. Epub 2011 Jul 19. 2011
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| 21 | HNA, SEPTIN9
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| Non-recurrent SEPT9 duplications cause hereditary neuralgic amyotrophy.
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| Collie AM, Landsverk ML, Ruzzo E, Mefford HC, Buysse K, Adkins JR, Knutzen DM, Barnett K, Brown RH Jr, Parry GJ, Yum SW, Simpson DA, Olney RK, Chinnery PF, Eichler EE, Chance PF, Hannibal MC.
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| J Med Genet 47(9):601-7. Epub 2009 Nov 25.PMID: 19939853 2010
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| 22 | SEPTIN9
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| Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission.
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| Estey MP, Di Ciano-Oliveira C, Froese CD, Bejide MT, Trimble WS.
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| J Cell Biol 191(4):741-9. doi: 10.1083/jcb.201006031. Epub 2010 Nov 8. 2010
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| 23 | SEPTIN9
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| Emergence of two unrelated clones in acute myeloid leukemia with MLL-SEPT9 fusion transcript.
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| Saito H, Otsubo K, Kakimoto A, Komatsu N, Ohsaka A.
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| Cancer Genet Cytogenet 201(2):111-5. doi: 10.1016/j.cancergencyto.2010.05.016. 2010
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| 24 | HNA, SEPTIN9
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| SEPT9 gene sequencing analysis reveals recurrent mutations in hereditary neuralgic amyotrophy.
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| Hannibal MC, Ruzzo EK, Miller LR, Betz B, Buchan JG, Knutzen DM, Barnett K, Landsverk ML, Brice A, LeGuern E, Bedford HM, Worrall BB, Lovitt S, Appel SH, Andermann E, Bird TD, Chance PF.
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| Neurology 72(20):1755-9. 2009
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| 25 | HNA, SEPTIN9
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| Duplication within the SEPT9 gene associated with a founder effect in North American families with hereditary neuralgic amyotrophy.
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| Landsverk ML, Ruzzo EK, Mefford HC, Buysse K, Buchan JG, Eichler EE, Petty EM, Peterson EA, Knutzen DM, Barnett K, Farlow MR, Caress J, Parry GJ, Quan D, Gardner KL, Hong M, Simmons Z, Bird TD, Chance PF, Hannibal MC.
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| Hum Mol Genet 18(7):1200-8. Epub 2009 Jan 12. 2009
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| 26 | SEPTIN9
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| Up-regulation of SEPT9_v1 stabilizes c-Jun-N-terminal kinase and contributes to its pro-proliferative activity in mammary epithelial cells.
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| Gonzalez ME, Makarova O, Peterson EA, Privette LM, Petty EM.
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| Cell Signal 21(4):477-87. Epub 2008 Nov 18. 2009
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| 27 | SEPTIN1, SEPTIN10, SEPTIN11, SEPTIN14, SEPTIN2, SEPTIN3, SEPTIN4, SEPTIN5, SEPTIN6, SEPTIN7, SEPTIN8, SEPTIN9
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| Structural and expression changes of septins in myeloid neoplasia.
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| Teixeira MR, Cerveira N, Santos J.
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| Crit Rev Oncog 15(1-2):91-115.PMID: 2013662 2009
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| 28 | SEPTIN11, SEPTIN6, SEPTIN7, SEPTIN8, SEPTIN9, SYP, VAMP2
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| Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin.
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| Ito H, Atsuzawa K, Morishita R, Usuda N, Sudo K, Iwamoto I, Mizutani K, Katoh-Semba R, Nozawa Y, Asano T, Nagata K.
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| J Neurochem 108(4):867-80. doi: 10.1111/j.1471-4159.2008.05849.x. Erratum in: J Neurochem. 2009 Mar;108(6):1621. 2009
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| 29 | HNA, SEPTIN8, SEPTIN9
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| Dysmorphic syndrome of hereditary neuralgic amyotrophy associated with a SEPT9 gene mutation--a family study.
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| Laccone F, Hannibal MC, Neesen J, Grisold W, Chance PF, Rehder H.
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| Clin Genet 74(3):279-83. Epub 2008 May 19. 2008
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| 30 | SEPTIN9
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| Translational control of SEPT9 isoforms is perturbed in disease.
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| McDade SS, Hall PA, Russell SE.
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| Hum Mol Genet 16(7):742-52. 2007
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| 31 | RTKN, SEPTIN11, SEPTIN4, SEPTIN9
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| SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling.
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| Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K.
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| Hum Mutat 28(10):1005-13. 2007
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| 32 | SEPTIN10, SEPTIN14, SEPTIN9
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| Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin.
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| Peterson EA, Kalikin LM, Steels JD, Estey MP, Trimble WS, Petty EM.
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| Mamm Genome 18(11):796-807. Epub 2007 Oct 6.PMID: 17922164 2007
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| 33 | KMT2A, SEPTIN9
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| Molecular dissection of t(11;17) in acute myeloid leukemia reveals a variety of gene fusions with heterogeneous fusion transcripts and multiple splice variants.
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| Strehl S, Konig M, Meyer C, Schneider B, Harbott J, Jager U, von Bergh AR, Loncarevic IF, Jarosova M, Schmidt HH, Moore SD, Marschalek R, Haas OA.
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| Genes Chromosomes Cancer 45(11):1041-9. 2006
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| 34 | SEPTIN9
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| Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours.
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| Scott M, Hyland PL, McGregor G, Hillan KJ, Russell SE, Hall PA.
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| Oncogene 24(29):4688-700. 2005
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| 35 | HNA, SEPTIN9
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| Mutations in SEPT9 cause hereditary neuralgic amyotrophy.
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| Kuhlenbaumer G, Hannibal MC, Nelis E, Schirmacher A, Verpoorten N, Meuleman J, Watts GD, Vriendt ED, Young P, Stogbauer F, Halfter H, Irobi J, Goossens D, Del-Favero J, Betz BG, Hor H, Kurlemann G, Bird TD, Airaksinen E, Mononen T, Serradell AP, Prats JM, Broeckhoven CV, Jonghe PD, Timmerman V, Ringelstein EB, Chance PF.
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| Nat Genet 37(10):1044-1046. Epub 2005 Sep 25. 2005
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| 36 | SEPTIN1, SEPTIN10, SEPTIN11, SEPTIN12, SEPTIN2, SEPTIN3, SEPTIN4, SEPTIN5, SEPTIN6, SEPTIN7, SEPTIN8, SEPTIN9, SEPTINP2
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| Expression profiling the human septin gene family.
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| Hall PA, Jung K, Hillan KJ, Russell SE.
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| J Pathol 206(3):269-78. 2005
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| 37 | SEPT7P2, SEPTIN1, SEPTIN10, SEPTIN11, SEPTIN12, SEPTIN2, SEPTIN3, SEPTIN4, SEPTIN5, SEPTIN6, SEPTIN7, SEPTIN8, SEPTIN9
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| The septins.
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| Kinoshita M.
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| Genome Biol 4(11):236. Epub 2003 Oct 27. Review. 2003
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| 38 | SEPTIN9
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| Alternative splicing, expression, and gene structure of the septin-like putative proto-oncogene Sint1.
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| Sorensen AB, Warming S, Fuchtbauer EM, Pedersen FS.
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| Gene 285(1-2):79-89. 2002
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| 39 | SEPTIN9
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| Fusion of MLL and MSF in adult de novo acute myelomonocytic leukemia (M4) with t(11;17)(q23;q25).
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| Yamamoto K, Shibata F, Yamaguchi M, Miura O.
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| Int J Hematol 75(5):503-7. 2002
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| 40 | SEPTIN9
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| Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3.
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| McIlhatton MA, Burrows JF, Donaghy PG, Chanduloy S, Johnston PG, Russell SE.
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| Oncogene 20(41):5930-9. 2001
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| 41 | SEPTIN9
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| Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors.
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| Russell SE, McIlhatton MA, Burrows JF, Donaghy PG, Chanduloy S, Petty EM, Kalikin LM, Church SW, McIlroy S, Harkin DP, Keilty GW, Cranston AN, Weissenbach J, Hickey I, Johnston PG.
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| Cancer Res 60(17):4729-34. 2000
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| 42 | FYB1, SEPTIN9
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| Genomic and expression analyses of alternatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors.
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| Kalikin LM, Sims HL, Petty EM.
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| Genomics 63(2):165-72. 2000
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| 43 | SEPTIN9
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| MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25).
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| Osaka M, et al.
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| Proc Natl Acad Sci U S A 96(11):6428-33. 1999
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| 44 | KMT2A, SEPTIN9
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| AF17q25, a putative septin family gene, fuses the MLL gene in acute myeloid leukemia with t(11;17)(q23;q25).
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| Taki T, Ohnishi H, Shinohara K, Sako M, Bessho F, Yanagisawa M, Hayashi Y.
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| Cancer Res 59(17):4261-5 1999
|