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FLASH GENE
Symbol HS3ST3A1 contributors: npt/ - updated : 12-02-2008
HGNC name heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HGNC id 5196
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 2546 44.8 406 - -
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   predominantly
Nervousbrain    
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta (predominantly)
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • five potential N glycosylation sites
  • four domains
  • a N terminal cytoplasmic tail
  • an hydrophobic transmembrane segment
  • a domain extremely rich in Ser, Pro, Leu, Ala, Gly (SPLAG domain,acting as a flexible stem and a putative C terminal catalytic domain)
    • HOMOLOGY
    interspecies homolog to murine Hs3st3a
    homolog to Drosophila CG7890
    homolog to C.elegans hst-3
    Homologene
    FAMILY
  • sulfotransferase 1 family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,lumen
    intracellular,cytoplasm,organelle,Golgi
    text integral membrane protein type II
    basic FUNCTION
  • heparan sulfate D-glucosamine 3-O-sulfotransferase 3A1
  • putative regulator of heparan sulfate proteoglycan properties
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS