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FLASH GENE
Symbol IL18R1 contributors: - updated : 23-02-2004
HGNC name interleukin 18 receptor 1
HGNC id 5988
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
transmembrane protein,characterized by a ligand binding domain composed of three Ig-like domains,and a short cytoplasmic domain required for signaling,homolog to Drosophila Toll (TIR domain)
HOMOLOGY
interspecies homolog to Drosophila Toll
homolog to IL-1 receptor protein
Homologene
FAMILY
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
text transmembrane protein
basic FUNCTION interleukin 18 receptor 1
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS immunity/defense
PATHWAY
metabolism
signaling signal transduction
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS