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FLASH GENE
Symbol IL18R1 contributors: - updated : 23-02-2004
HGNC name interleukin 18 receptor 1
HGNC id 5988
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 36.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
CREG2 2q11.2 hypothetical protein FLJ30294 LOC389012 2 similar to hypothetical protein MGC33442 LOC389013 2 LOC389013 LOC389014 2 LOC389014 LOC391411 2 similar to ribosomal protein S6 LOC391412 2 similar to Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase) (Angiotensinase C) (Lysosomal carboxypeptidase C) MAP4K4 2q11.2 mitogen-activated protein kinase kinase kinase kinase 4 FLJ20373 2q12.1 hypothetical protein FLJ20373 IL1R2 2q12 interleukin 1 receptor, type II IL1R1 2q12 interleukin 1 receptor, type I IL1RL2 2q12 interleukin 1 receptor-like 2 IL1RL1 2q12 interleukin 1 receptor-like 1 IL18R1 2q12 interleukin 18 receptor 1 IL18RAP 2p24.3-p24.1 interleukin 18 receptor accessory protein LOC389015 2 similar to Sodium/hydrogen exchanger 4 (Na(+)/H(+) exchanger 4) (NHE-4) SLC9A2 2q11.2 solute carrier family 9 (sodium/hydrogen exchanger), isoform 2 MGC11332 2q12.1 hypothetical protein MGC11332 FLJ30294 2q12.1 hypothetical protein FLJ30294
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
transmembrane protein,characterized by a ligand binding domain composed of three Ig-like domains,and a short cytoplasmic domain required for signaling,homolog to Drosophila Toll (TIR domain)
HOMOLOGY
interspecies homolog to Drosophila Toll
homolog to IL-1 receptor protein
Homologene
FAMILY
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
text transmembrane protein
basic FUNCTION interleukin 18 receptor 1
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS immunity/defense
PATHWAY
metabolism
signaling signal transduction
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS