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FLASH GENE

Symbol

IL18R1

contributors: - updated : 23-02-2004

HGNC name	interleukin 18 receptor 1
HGNC id	5988

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
STRUCTURE	36.00 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver         Respiratory lung

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

transmembrane protein,characterized by a ligand binding domain composed of three Ig-like domains,and a short cytoplasmic domain required for signaling,homolog to Drosophila Toll (TIR domain)

HOMOLOGY

interspecies	homolog to Drosophila Toll
	homolog to IL-1 receptor protein

Homologene

FAMILY

CATEGORY

receptor

SUBCELLULAR LOCALIZATION	plasma membrane
text	transmembrane protein

basic FUNCTION

interleukin 18 receptor 1

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

immunity/defense

PATHWAY

metabolism

signaling

signal transduction

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS