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FLASH GENE
Symbol BRD8 contributors: - updated : 17-09-2004
HGNC name bromodomain containing 8
HGNC id 19874
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • bromodomains,several potential sites for phosphorylation by casein kinase II and small proline-rich segments
    • HOMOLOGY
    interspecies ortholog to murine 2610007e11Rik
    Homologene
    FAMILY
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • thyroid hormone receptor coactivator protein
  • ligand-regulated transcription factor
  • enhancing thyroid hormone-dependent activation from thyroid
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component response elements (TREs)
    INTERACTION
    DNA
    RNA
    small molecule
    protein thyroid hormone receptor in a ligand-dependent manner
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS