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FLASH GENE
Symbol BRD8 contributors: - updated : 17-09-2004
HGNC name bromodomain containing 8
HGNC id 19874
DNA
TYPE functioning gene
STRUCTURE 38.00 kb     29 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3253 - 951 - Lai
- - 4074 - 1235 - Lai
- - 3086 81.3 757 - Lai
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • bromodomains,several potential sites for phosphorylation by casein kinase II and small proline-rich segments
  • HOMOLOGY
    interspecies ortholog to murine 2610007e11Rik
    Homologene
    FAMILY
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • thyroid hormone receptor coactivator protein
  • ligand-regulated transcription factor
  • enhancing thyroid hormone-dependent activation from thyroid
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component response elements (TREs)
    INTERACTION
    DNA
    RNA
    small molecule
    protein thyroid hormone receptor in a ligand-dependent manner
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS