| basic FUNCTION
| involving in neuron-specific splicing of the N1 exon of SRC |
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inducing the assembly of five other proteins, including the heterogeneous nuclear ribonucleoprotein F, onto the splicing enhancer |
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may be playing a role in nucleocytoplasmic mRNA targeting |
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having functions as a limiting factor in inflammatory gene expression |
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multifunctional RNA-binding protein that has been implicated in transcriptional regulation, neuro-specific alternative splicing and mRNA decay |
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involved in the etiology of milder forms of SMA |
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multi-domain RNA-binding protein that recruits the exosome-containing mRNA degradation complex to mRNAs coding for cellular proliferation and inflammatory response factors  |
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with HNRNPA1 have antagonistic roles in the post-transcriptional regulation of MIRLET7A1, MIRLET7A2, MIRLET7A3 expression |
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function of KHSRP in innate immunity by negatively regulating IFN production |
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critical role for KHSRP in regulating pro-inflammatory mediators and have implications for a wide range of CNS inflammatory and autoimmune diseases |
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likely involved in Schwann cells (SCs) and neuronal differentiation by inducing CTNNB1 mRNA decay |
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ability of KHSRP to integrate different levels of gene expression is required for proper immune response, lipid metabolism, cell-fate decisions, tissue regeneration, and DNA damage response |
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KHSRP is an important regulator of circadian expression of lipid metabolism genes in the liver likely through controlling PER2 mRNA stability |
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controls important cellular functions as different as proliferation, differentiation, metabolism, and response to infectious agents |
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likely oncogenic role for KHSRP in lung cancer |
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is a nucleic acid binding protein, which negatively regulates the stability and/or translatability of many mRNA species encoding immune-relevant proteins |
