Citations for
1KHSRP, SPRY4
K-homology splicing regulatory protein (KSRP) promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer.
Bikkavilli RK, Zerayesus SA, Van Scoyk M, Wilson L, Wu PY, Baskaran A, Tang K, Raheem S, Samuelson BA, Reddy NM, Reddy SP, Cool CD, Kosmider B, Avasarala S, Winn RA.
J Biol Chem 292(18):7423-7434. doi: 10.1074/jbc.M116.757906. Epub 2017 Mar 8. 2017
2KHSRP, KLHL12
Control of the negative IRES trans-acting factor KHSRP by ubiquitination.
Kung YA, Hung CT, Chien KY, Shih SR.
Nucleic Acids Res 45(1):271-287. doi: 10.1093/nar/gkw1042. Epub 2016 Nov 28. 2017
3KHSRP
Inactivation of the KSRP gene modifies collagen antibody induced arthritis.
Käfer R, Schrick K, Schmidtke L, Montermann E, Hobernik D, Bros M, Chen CY, Kleinert H, Pautz A.
Mol Immunol 87:207-216. doi: 10.1016/j.molimm.2017.05.003. Epub 2017 May 13. 2017
4AGO2, DDX17, KHSRP
The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.
Connerty P, Bajan S, Remenyi J, Fuller-Pace FV, Hutvagner G.
Biochim Biophys Acta 1859(10):1299-305. doi: 10.1016/j.bbagrm.2016.07.013. Epub 2016 Jul 28. 2016
5KHSRP, PTH, SLC34A1
Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA.
Murray RD, Merchant ML, Hardin E, Clark B, Khundmiri SJ, Lederer ED.
Am J Physiol Cell Physiol 310(3):C205-15. doi: 10.1152/ajpcell.00192.2015. Epub 2015 Nov 25. 2016
6KHSRP
Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease.
Briata P, Bordo D, Puppo M, Gorlero F, Rossi M, Perrone-Bizzozero N, Gherzi R.
Wiley Interdiscip Rev RNA 7(2):227-40. doi: 10.1002/wrna.1327. Epub 2015 Dec 27. Review. 2016
7KHSRP, PER2
KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression.
Chou CF, Zhu X, Lin YY, Gamble KL, Garvey WT, Chen CY.
J Lipid Res 56(2):227-40. doi: 10.1194/jlr.M050724. Epub 2014 Dec 16. 2015
8KHSRP
KSRP controls pleiotropic cellular functions.
Gherzi R, Chen CY, Ramos A, Briata P.
Semin Cell Dev Biol 34:2-8. doi: 10.1016/j.semcdb.2014.05.004. Epub 2014 May 17. Review. 2014
9KHSRP
Spatiotemporal expression of KHSRP modulates Schwann cells and neuronal differentiation after sciatic nerve injury.
Zhu X, Yao L, Yang X, Sun H, Guo A, Li A, Yang H.
Int J Biochem Cell Biol 48:1-10. doi: 10.1016/j.biocel.2013.12.008. Epub 2013 Dec 22. 2014
10DDX1, KHSRP
DEAD box protein DDX1 regulates cytoplasmic localization of KSRP.
Chou CF, Lin WJ, Lin CC, Luber CA, Godbout R, Mann M, Chen CY.
PLoS One 8(9):e73752. doi: 10.1371/journal.pone.0073752. 2013
11ELAVL4, GAP43, KHSRP
KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.
Bird CW, Gardiner AS, Bolognani F, Tanner DC, Chen CY, Lin WJ, Yoo S, Twiss JL, Perrone-Bizzozero N.
PLoS One 8(11):e79255. doi: 10.1371/journal.pone.0079255. eCollection 2013. 2013
12KHSRP
KSRP: a checkpoint for inflammatory cytokine production in astrocytes.
Li X, Lin WJ, Chen CY, Si Y, Zhang X, Lu L, Suswam E, Zheng L, King PH.
Glia 60(11):1773-84. doi: 10.1002/glia.22396. Epub 2012 Jul 28. 2012
13KHSRP
Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism.
Dhamija S, Kuehne N, Winzen R, Doerrie A, Dittrich-Breiholz O, Thakur BK, Kracht M, Holtmann H.
J Biol Chem 286(38):33279-88. doi: 10.1074/jbc.M111.264754. Epub 2011 Jul 27. 2011
14KHSRP
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection.
Lin WJ, Zheng X, Lin CC, Tsao J, Zhu X, Cody JJ, Coleman JM, Gherzi R, Luo M, Townes TM, Parker JN, Chen CY.
Mol Cell Biol 31(16):3196-207. doi: 10.1128/MCB.05073-11. Epub 2011 Jun 20. 2011
15KHSRP
Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.
Díaz-Moreno I, Hollingworth D, Kelly G, Martin S, García-Mayoral M, Briata P, Gherzi R, Ramos A.
Nucleic Acids Res 38(15):5193-205. Epub 2010 Apr 12. 2010
16HNRNPA1, KHSRP
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis.
Michlewski G, Cáceres JF.
Nat Struct Mol Biol 17(8):1011-8. Epub 2010 Jul 18. 2010
17KHSRP, YWHAZ
Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.
Díaz-Moreno I, Hollingworth D, Frenkiel TA, Kelly G, Martin S, Howell S, García-Mayoral M, Gherzi R, Briata P, Ramos A.
Nat Struct Mol Biol 16(3):238-46. Epub 2009 Feb 8. 2009
18FUBP1, KHSRP
Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth.
Rabenhorst U, Beinoraviciute-Kellner R, Brezniceanu ML, Joos S, Devens F, Lichter P, Rieker RJ, Trojan J, Chung HJ, Levens DL, Zörnig M.
Hepatology 50(4):1121-9.PMID: 19637194 2009
19FUBP1, KHSRP
Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.
Malz M, Weber A, Singer S, Riehmer V, Bissinger M, Riener MO, Longerich T, Soll C, Vogel A, Angel P, Schirmacher P, Breuhahn K.
Hepatology 50(4):1130-9.PMID: 19585652 2009
20KHSRP, SMA, SMN1
KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy.
Tadesse H, Deschnes-Furry J, Boisvenue S, C™tŽ J.
Hum Mol Genet 17(4):506-24. Epub 2007 Nov 12. 2008
21KHSRP, PGK2
A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells.
Xu M, McCarrey JR, Hecht NB.
Nucleic Acids Res 36(22):7157-67. Epub 2008 Nov 10. 2008
22KHSRP
Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets.
Winzen R, Thakur BK, Dittrich-Breiholz O, Shah M, Redich N, Dhamija S, Kracht M, Holtmann H.
Mol Cell Biol 27(23):8388-400. Epub 2007 Oct 1. 2007
23AKT2, COX6B1, DAPK3, ETV2, KHSRP, OR7A10, OR7A5, OR7D2, OR7E24, S1PR5, ZNF607, ZNF610, ZSCAN5C
The DNA sequence and biology of human chromosome 19.
Grimwood J, and al.
Nature 428(6982):529-35. 2004
24KHSRP
Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17.
Ring HZ, et al.
Genomics 56(3):350-2. 1999
25KHSRP
A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.
Min H, Turck CW, Nikolic JM, Black DL.
Genes Dev 11(8):1023-36. 1997
26FUBP3, KHSRP
The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.
Davis-Smyth T, Duncan RC, Zheng T, Michelotti G, Levens D.
J Biol Chem 271(49):31679-87. 1996