1 | KHSRP, SPRY4
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| K-homology splicing regulatory protein (KSRP) promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer.
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| Bikkavilli RK, Zerayesus SA, Van Scoyk M, Wilson L, Wu PY, Baskaran A, Tang K, Raheem S, Samuelson BA, Reddy NM, Reddy SP, Cool CD, Kosmider B, Avasarala S, Winn RA.
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| J Biol Chem 292(18):7423-7434. doi: 10.1074/jbc.M116.757906. Epub 2017 Mar 8.
2017
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2 | KHSRP, KLHL12
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| Control of the negative IRES trans-acting factor KHSRP by ubiquitination.
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| Kung YA, Hung CT, Chien KY, Shih SR.
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| Nucleic Acids Res 45(1):271-287. doi: 10.1093/nar/gkw1042. Epub 2016 Nov 28.
2017
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3 | KHSRP
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| Inactivation of the KSRP gene modifies collagen antibody induced arthritis.
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| Käfer R, Schrick K, Schmidtke L, Montermann E, Hobernik D, Bros M, Chen CY, Kleinert H, Pautz A.
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| Mol Immunol 87:207-216. doi: 10.1016/j.molimm.2017.05.003. Epub 2017 May 13.
2017
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4 | AGO2, DDX17, KHSRP
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| The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.
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| Connerty P, Bajan S, Remenyi J, Fuller-Pace FV, Hutvagner G.
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| Biochim Biophys Acta 1859(10):1299-305. doi: 10.1016/j.bbagrm.2016.07.013. Epub 2016 Jul 28.
2016
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5 | KHSRP, PTH, SLC34A1
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| Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA.
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| Murray RD, Merchant ML, Hardin E, Clark B, Khundmiri SJ, Lederer ED.
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| Am J Physiol Cell Physiol 310(3):C205-15. doi: 10.1152/ajpcell.00192.2015. Epub 2015 Nov 25.
2016
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6 | KHSRP
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| Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease.
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| Briata P, Bordo D, Puppo M, Gorlero F, Rossi M, Perrone-Bizzozero N, Gherzi R.
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| Wiley Interdiscip Rev RNA 7(2):227-40. doi: 10.1002/wrna.1327. Epub 2015 Dec 27. Review.
2016
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7 | KHSRP, PER2
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| KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression.
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| Chou CF, Zhu X, Lin YY, Gamble KL, Garvey WT, Chen CY.
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| J Lipid Res 56(2):227-40. doi: 10.1194/jlr.M050724. Epub 2014 Dec 16.
2015
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8 | KHSRP
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| KSRP controls pleiotropic cellular functions.
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| Gherzi R, Chen CY, Ramos A, Briata P.
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| Semin Cell Dev Biol 34:2-8. doi: 10.1016/j.semcdb.2014.05.004. Epub 2014 May 17. Review.
2014
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9 | KHSRP
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| Spatiotemporal expression of KHSRP modulates Schwann cells and neuronal differentiation after sciatic nerve injury.
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| Zhu X, Yao L, Yang X, Sun H, Guo A, Li A, Yang H.
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| Int J Biochem Cell Biol 48:1-10. doi: 10.1016/j.biocel.2013.12.008. Epub 2013 Dec 22.
2014
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10 | DDX1, KHSRP
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| DEAD box protein DDX1 regulates cytoplasmic localization of KSRP.
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| Chou CF, Lin WJ, Lin CC, Luber CA, Godbout R, Mann M, Chen CY.
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| PLoS One 8(9):e73752. doi: 10.1371/journal.pone.0073752.
2013
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11 | ELAVL4, GAP43, KHSRP
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| KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.
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| Bird CW, Gardiner AS, Bolognani F, Tanner DC, Chen CY, Lin WJ, Yoo S, Twiss JL, Perrone-Bizzozero N.
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| PLoS One 8(11):e79255. doi: 10.1371/journal.pone.0079255. eCollection 2013.
2013
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12 | KHSRP
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| KSRP: a checkpoint for inflammatory cytokine production in astrocytes.
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| Li X, Lin WJ, Chen CY, Si Y, Zhang X, Lu L, Suswam E, Zheng L, King PH.
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| Glia 60(11):1773-84. doi: 10.1002/glia.22396. Epub 2012 Jul 28.
2012
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13 | KHSRP
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| Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism.
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| Dhamija S, Kuehne N, Winzen R, Doerrie A, Dittrich-Breiholz O, Thakur BK, Kracht M, Holtmann H.
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| J Biol Chem 286(38):33279-88. doi: 10.1074/jbc.M111.264754. Epub 2011 Jul 27.
2011
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14 | KHSRP
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| Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection.
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| Lin WJ, Zheng X, Lin CC, Tsao J, Zhu X, Cody JJ, Coleman JM, Gherzi R, Luo M, Townes TM, Parker JN, Chen CY.
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| Mol Cell Biol 31(16):3196-207. doi: 10.1128/MCB.05073-11. Epub 2011 Jun 20.
2011
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15 | KHSRP
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| Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.
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| Díaz-Moreno I, Hollingworth D, Kelly G, Martin S, García-Mayoral M, Briata P, Gherzi R, Ramos A.
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| Nucleic Acids Res 38(15):5193-205. Epub 2010 Apr 12.
2010
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16 | HNRNPA1, KHSRP
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| Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis.
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| Michlewski G, Cáceres JF.
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| Nat Struct Mol Biol 17(8):1011-8. Epub 2010 Jul 18. 2010
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17 | KHSRP, YWHAZ
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| Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.
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| Díaz-Moreno I, Hollingworth D, Frenkiel TA, Kelly G, Martin S, Howell S, García-Mayoral M, Gherzi R, Briata P, Ramos A.
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| Nat Struct Mol Biol 16(3):238-46. Epub 2009 Feb 8.
2009
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18 | FUBP1, KHSRP
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| Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth.
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| Rabenhorst U, Beinoraviciute-Kellner R, Brezniceanu ML, Joos S, Devens F, Lichter P, Rieker RJ, Trojan J, Chung HJ, Levens DL, Zörnig M.
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| Hepatology 50(4):1121-9.PMID: 19637194 2009
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19 | FUBP1, KHSRP
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| Overexpression of far upstream element binding proteins: a mechanism regulating proliferation and migration in liver cancer cells.
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| Malz M, Weber A, Singer S, Riehmer V, Bissinger M, Riener MO, Longerich T, Soll C, Vogel A, Angel P, Schirmacher P, Breuhahn K.
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| Hepatology 50(4):1130-9.PMID: 19585652 2009
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20 | KHSRP, SMA, SMN1
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| KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy.
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| Tadesse H, Deschnes-Furry J, Boisvenue S, C™tŽ J.
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| Hum Mol Genet 17(4):506-24. Epub 2007 Nov 12. 2008
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21 | KHSRP, PGK2
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| A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells.
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| Xu M, McCarrey JR, Hecht NB.
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| Nucleic Acids Res 36(22):7157-67. Epub 2008 Nov 10.
2008
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22 | KHSRP
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| Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets.
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| Winzen R, Thakur BK, Dittrich-Breiholz O, Shah M, Redich N, Dhamija S, Kracht M, Holtmann H.
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| Mol Cell Biol 27(23):8388-400. Epub 2007 Oct 1. 2007
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23 | AKT2, COX6B1, DAPK3, ETV2, KHSRP, OR7A10, OR7A5, OR7D2, OR7E24, S1PR5, ZNF607, ZNF610, ZSCAN5C
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| The DNA sequence and biology of human chromosome 19.
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| Grimwood J, and al.
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| Nature 428(6982):529-35. 2004
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24 | KHSRP
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| Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17.
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| Ring HZ, et al.
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| Genomics 56(3):350-2. 1999
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25 | KHSRP
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| A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.
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| Min H, Turck CW, Nikolic JM, Black DL.
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| Genes Dev 11(8):1023-36. 1997
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26 | FUBP3, KHSRP
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| The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.
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| Davis-Smyth T, Duncan RC, Zheng T, Michelotti G, Levens D.
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| J Biol Chem 271(49):31679-87. 1996
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