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FLASH GENE
Symbol CDIPT contributors: - updated : 24-06-2005
HGNC name CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
HGNC id 1769
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to goat polledness and intersexuality gene
homolog to Drosophila CG9245
homolog to C.elegans Y46G5A.5
Homologene
FAMILY member of the CDP-alcohol phosphatidyl transferase class-I family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
intracellular,cytoplasm,organelle,Golgi
text an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus
basic FUNCTION having both phosphatidylinositol synthase and phosphatidylinositol :inositol exchange activity
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS cellular trafficking transport
text phosphatidylinositol transporter
PATHWAY
metabolism lipid/lipoprotein
signaling
phospholipid biosynthesis
a component
INTERACTION
DNA
RNA
small molecule metal binding, cofactor,
magnesium Mg2+,manganese Mn2+
protein
cell & other
REGULATION
inhibited by phosphatidylinositol,phosphatidylinositol phosphate and nucleoside di- and tri- phosphates
calcium Ca2+ and zinc Zn2+
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS