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FLASH GENE
Symbol CAV1 contributors: mct/shn - updated : 16-03-2018
HGNC name caveolin 1, caveolae protein, 22kDa
HGNC id 1527
ANIMAL & CELL MODELS
  • Caveolin-1 null mice display hyperproliferative and vascular abnormalities (
  • mice disrupted for Cav1 display vascular dysfunction and pulmonary defects (
  • Cav-1(-/-) mice displayed a decreased percentage of B cells and an increased percentage of M cells in the bone marrow and peripheral blood, and these changes were due to an increased number of HSCs
  • mice deficient in the Cav1 gene have no caveolae structures in several nonmuscle cell types, a dilated cardiomyopathy in the left ventricular chamber including an enlarged ventricular chamber diameter and a ventricular hypertrophy (
  • genetic depletion of caveolin-1 in fibroblasts abolished the antiproliferative effect of carbon monoxide (
  • caveolin-1 gene-disrupted mice display impaired liver regeneration and low survival after a partial hepatectomy (