| 1 | CAV1, SPG8, WASHC5
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| Hereditary spastic paraplegia SPG8 mutations impair CAV1-dependent, integrin-mediated cell adhesion. 2020
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| Lee S, Park H, Zhu PP, Jung SY, Blackstone C, Chang J
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| Sci Signal. Jan 7;13(613):eaau7500. doi: 10.1126/scisignal.aau7500 2020
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| 2 | CAV1, TLR4, ZNRF1
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| The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.
|
| Lee CY, Lai TY, Tsai MK, Chang YC, Ho YH, Yu IS, Yeh TW, Chou CC, Lin YS, Lawrence T, Hsu LC.
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| Nat Commun 8:15502. doi: 10.1038/ncomms15502.
2017
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| 3 | CAV1, FABP5, SEPTIN11
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| The cytoskeletal protein septin 11 is associated with human obesity and is involved in adipocyte lipid storage and metabolism.
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| Moreno-Castellanos N, Rodríguez A, Rabanal-Ruiz Y, Fernández-Vega A, López-Miranda J, Vázquez-Martínez R, Frühbeck G, Malagón MM.
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| Diabetologia 60(2):324-335. doi: 10.1007/s00125-016-4155-5. Epub 2016 Nov 19.
2017
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| 4 | CAV1, SLC1A1, SLC1A2, SLC1A3, SLC1A6
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| Caveolin-1 Sensitivity of Excitatory Amino Acid Transporters EAAT1, EAAT2, EAAT3, and EAAT4.
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| Abousaab A, Warsi J, Elvira B, Lang F.
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| J Membr Biol 249(3):239-49. doi: 10.1007/s00232-015-9863-0. Epub 2015 Dec 21.
2016
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| 5 | CAV1, RNF213
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| Caveolin-1, Ring finger protein 213, and endothelial function in Moyamoya disease.
|
| Bang OY, Chung JW, Kim SJ, Oh MJ, Kim SY, Cho YH, Cha J, Yeon JY, Kim KH, Kim GM, Chung CS, Lee KH, Ki CS, Jeon P, Kim JS, Hong SC, Moon GJ.
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| Int J Stroke 11(9):999-1008.
2016
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| 6 | CAV1, TGFB1
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| Internalization of the TGF-β type I receptor into caveolin-1 and EEA1 double-positive early endosomes.
|
| He K, Yan X, Li N, Dang S, Xu L, Zhao B, Li Z, Lv Z, Fang X, Zhang Y, Chen YG.
|
| Cell Res 25(6):738-52. doi: 10.1038/cr.2015.60. Epub 2015 May 22.
2015
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| 7 | CAV1
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| Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy.
|
| Shi Y, Tan SH, Ng S, Zhou J, Yang ND, Koo GB, McMahon KA, Parton RG, Hill MM, Del Pozo MA, Kim YS, Shen HM.
|
| Autophagy 11(5):769-84. doi: 10.1080/15548627.2015.1034411.
2015
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| 8 | CAV1
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| Caveolin-1 Deficiency Inhibits the Basolateral K+ Channels in the Distal Convoluted Tubule and Impairs Renal K+ and Mg2+ Transport.
|
| Wang L, Zhang C, Su X, Lin DH, Wang W.
|
| J Am Soc Nephrol 26(11):2678-90. doi: 10.1681/ASN.2014070658. Epub 2015 Apr 6.
2015
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| 9 | CAV1, PTRF
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| Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma.
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| Faggi F, Chiarelli N, Colombi M, Mitola S, Ronca R, Madaro L, Bouche M, Poliani PL, Vezzoli M, Longhena F, Monti E, Salani B, Maggi D, Keller C, Fanzani A.
|
| Lab Invest 95(6):585-602. doi: 10.1038/labinvest.2015.45. Epub 2015 Mar 30.
2015
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| 10 | CAV1
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| Caveolin-1 phosphorylation regulates vascular endothelial insulin uptake and is impaired by insulin resistance in rats.
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| Wang H, Wang AX, Aylor K, Barrett EJ.
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| Diabetologia 58(6):1344-53. doi: 10.1007/s00125-015-3546-3. Epub 2015 Mar 10.
2015
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| 11 | CAV1, PTPN11
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| Protein-protein interaction between caveolin-1 and SHP-2 is dependent on the N-SH2 domain of SHP-2.
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| Park H, Ahn KJ, Lee Kang J, Choi YH.
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| BMB Rep 48(3):184-9.
2015
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| 12 | CAV1
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| Distinct structural domains of caveolin-1 independently regulate Ca2+ release-activated Ca2+ channels and Ca2+ microdomain-dependent gene expression.
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| Yeh YC, Parekh AB.
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| Mol Cell Biol 35(8):1341-9. doi: 10.1128/MCB.01068-14. Epub 2015 Feb 2.
2015
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| 13 | CAV1, PTFR
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| PTRF is associated with caveolin 1 at the time of receptivity: but SDPR is absent at the same time.
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| Madawala RJ, Poon CE, Dowland SN, Murphy CR.
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| Histochem Cell Biol 143(6):637-44. doi: 10.1007/s00418-015-1308-4. Epub 2015 Jan 25.
2015
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| 14 | CAV1, ESR1
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| Increased coupling of caveolin-1 and estrogen receptor α contributes to the fragile X syndrome.
|
| Yang Q, Yang L, Zhang K, Guo YY, Liu SB, Wu YM, Li XQ, Song Q, Zhuo M, Zhao MG.
|
| Ann Neurol 77(4):618-36. doi: 10.1002/ana.24358. Epub 2015 Feb 26.
2015
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| 15 | CAV1, PRKCDBP, PTRF
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| Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae.
|
| Mohan J, Morén B, Larsson E, Holst MR, Lundmark R.
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| J Cell Sci 128(5):979-91. doi: 10.1242/jcs.161463. Epub 2015 Jan 14.
2015
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| 16 | CAV1
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| Caveolin-1 regulates osteoclastogenesis and bone metabolism in a sex-dependent manner.
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| Lee YD, Yoon SH, Park CK, Lee J, Lee ZH, Kim HH.
|
| J Biol Chem 290(10):6522-30. doi: 10.1074/jbc.M114.598581. Epub 2015 Jan 5.
2015
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| 17 | CAV1, P2RX7
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| Caveolin-1 regulates P2X7 receptor signaling in osteoblasts.
|
| Gangadharan V, Nohe A, Caplan J, Czymmek K, Duncan RL.
|
| Am J Physiol Cell Physiol 308(1):C41-50. doi: 10.1152/ajpcell.00037.2014. Epub 2014 Oct 15.
2015
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| 18 | CAV1, MRTFB, MYOCD
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| Myocardin Family Members Drive Formation of Caveolae.
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| Krawczyk KK, Yao Mattisson I, Ekman M, Oskolkov N, Grantinge R, Kotowska D, Olde B, Hansson O, Albinsson S, Miano JM, Rippe C, Swärd K.
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| PLoS One 10(8):e0133931. doi: 10.1371/journal.pone.0133931. eCollection 2015. 2015
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| 19 | CAMK2A, CAMK2B, CAV1, PDIA3, PLAA
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| Membrane-mediated actions of 1,25-dihydroxy vitamin D3: a review of the roles of phospholipase A2 activating protein and Ca(2+)/calmodulin-dependent protein kinase II.
|
| Doroudi M, Schwartz Z, Boyan BD.
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| J Steroid Biochem Mol Biol 147:81-4. doi: 10.1016/j.jsbmb.2014.11.002. Epub 2014 Nov 6. Review. 2015
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| 20 | ADAM17, CAV1
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| Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17.
|
| Moreno-Cŕceres J, Caja L, Mainez J, Mayoral R, Martín-Sanz P, Moreno-Vicente R, Del Pozo MÁ, Dooley S, Egea G, Fabregat I.
|
| Cell Death Dis 5:e1326. doi: 10.1038/cddis.2014.294.
2014
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| 21 | CAV1
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| Caveolin-1 and ATP binding cassette transporter A1 and G1-mediated cholesterol efflux.
|
| Wang F, Gu HM, Zhang DW.
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| Cardiovasc Hematol Disord Drug Targets 14(2):142-8. Review.
2014
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| 22 | CAV1
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| Expression of Caveolin 1 is enhanced by DNA demethylation during adipocyte differentiation. status of insulin signaling.
|
| Palacios-Ortega S, Varela-Guruceaga M, Milagro FI, Martínez JA, de Miguel C.
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| PLoS One 9(4):e95100. doi: 10.1371/journal.pone.0095100. eCollection 2014.
2014
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| 23 | CAV1
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| Cav-1 deletion impaired hematopoietic stem cell function.
|
| Bai L, Shi G, Zhang L, Guan F, Ma Y, Li Q, Cong YS, Zhang L.
|
| Cell Death Dis 5:e1140. doi: 10.1038/cddis.2014.105.
2014
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| 24 | ABCG1, CAV1
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| Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux.
|
| Gu HM, Wang FQ, Zhang DW.
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| Biochim Biophys Acta 1841(6):847-58. doi: 10.1016/j.bbalip.2014.02.002. Epub 2014 Feb 24.
2014
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| 25 | AGT, CAV1
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| Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase.
|
| Takayanagi T, Crawford KJ, Kobayashi T, Obama T, Tsuji T, Elliott KJ, Hashimoto T, Rizzo V, Eguchi S.
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| Clin Sci (Lond) 126(11):785-94. doi: 10.1042/CS20130660.
2014
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| 26 | CAV1, PTRF
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| Cavin-1 is essential for the tumor-promoting effect of caveolin-1 and enhances its prognostic potency in pancreatic cancer.
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| Liu L, Xu HX, Wang WQ, Wu CT, Chen T, Qin Y, Liu C, Xu J, Long J, Zhang B, Xu YF, Ni QX, Li M, Yu XJ.
|
| Oncogene 33(21):2728-36. doi: 10.1038/onc.2013.223. Epub 2013 Jun 17.
2014
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| 27 | CAV1, VCP
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| Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase.
|
| Kirchner P, Bug M, Meyer H.
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| J Biol Chem 288(10):7363-72. doi: 10.1074/jbc.M112.429076. Epub 2013 Jan 19.
2013
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| 28 | CAV1, PPP5C
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| Caveolin-1 interacts with protein phosphatase 5 and modulates its activity in prostate cancer cells.
|
| Taira J, Higashimoto Y.
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| Biochem Biophys Res Commun 431(4):724-8. doi: 10.1016/j.bbrc.2013.01.051. Epub 2013 Jan 23.
2013
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| 29 | CAV1, DERL1, PTGS2
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| Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex.
|
| Chen SF, Wu CH, Lee YM, Tam K, Tsai YC, Liou JY, Shyue SK.
|
| J Biol Chem 288(46):33462-9. doi: 10.1074/jbc.M113.521799. Epub 2013 Oct 2.
2013
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| 30 | CAV1
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| Intestinal caveolin-1 is important for dietary fatty acid absorption.
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| Siddiqi S, Sheth A, Patel F, Barnes M, Mansbach CM 2nd.
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| Biochim Biophys Acta 1831(8):1311-21. doi: 10.1016/j.bbalip.2013.05.001. Epub 2013 May 7.
2013
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| 31 | CAV1, KRAS
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| Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis.
|
| Basu Roy UK, Henkhaus RS, Loupakis F, Cremolini C, Gerner EW, Ignatenko NA.
|
| Int J Cancer 133(1):43-57. doi: 10.1002/ijc.28001. Epub 2013 Feb 12. Erratum in: Int J Cancer. 2015 Oct 15;137(8):E18.
2013
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| 32 | CAV1, PRKCDBP, PTRF, SDPR
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| Deletion of cavin genes reveals tissue-specific mechanisms for morphogenesis of endothelial caveolae.
|
| Hansen CG, Shvets E, Howard G, Riento K, Nichols BJ.
|
| Nat Commun 4:1831. doi: 10.1038/ncomms2808.
2013
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| 33 | CAV1, DLC1
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| Functional interaction of tumor suppressor DLC1 and caveolin-1 in cancer cells.
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| Du X, Qian X, Papageorge A, Schetter AJ, Vass WC, Liu X, Braverman R, Robles AI, Lowy DR.
|
| Cancer Res 72(17):4405-16. doi: 10.1158/0008-5472.CAN-12-0777. Epub 2012 Jun 12.
2012
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| 34 | CAV1, DSG2
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| A role for caveolin-1 in desmoglein binding and desmosome dynamics.
|
| Brennan D, Peltonen S, Dowling A, Medhat W, Green KJ, Wahl JK 3rd, Del Galdo F, Mahoney MG.
|
| Oncogene 31(13):1636-48. doi: 10.1038/onc.2011.346. Epub 2011 Aug 15.
2012
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| 35 | CAV1
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| Calcium regulates caveolin-1 expression at the transcriptional level.
|
| Yang XY, Huang CC, Kan QM, Li Y, Liu D, Zhang XC, Sato T, Yamagata S, Yamagata T.
|
| Biochem Biophys Res Commun 426(3):334-41. doi: 10.1016/j.bbrc.2012.08.079. Epub 2012 Aug 23.
2012
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| 36 | CAV1, CAV2
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| Chromosome 7q31 POAG locus: ocular expression of caveolins and lack of association with POAG in a US cohort.
|
| Kuehn MH, Wang K, Roos B, Stone EM, Kwon YH, Alward WL, Mullins RF, Fingert JH.
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| Mol Vis. 17:430-5. 2011
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| 37 | CAV1, PAG1, SRC
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| Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src.
|
| Place AT, Chen Z, Bakhshi FR, Liu G, O'Bryan JP, Minshall RD.
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| Mol Pharmacol 80(4):665-72. Epub 2011 Jul 21.
2011
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| 38 | CAV1
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| Loss of stromal caveolin-1 expression in malignant melanoma metastases predicts poor survival.
|
| Wu KN, Queenan M, Brody JR, Potoczek M, Sotgia F, Lisanti MP, Witkiewicz AK.
|
| Cell Cycle 10(24):4250-5. doi: 10.4161/cc.10.24.18551. Epub 2011 Dec 15.
2011
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| 39 | BID, CAV1
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| Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis.
|
| Zhang M, Lee SJ, An C, Xu JF, Joshi B, Nabi IR, Choi AM, Jin Y.
|
| Free Radic Biol Med 50(10):1252-62. doi: 10.1016/j.freeradbiomed.2011.02.031. Epub 2011 Mar 5.
2011
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| 40 | CAV1, CD109, TGFB1
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| The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors.
|
| Bizet AA, Liu K, Tran-Khanh N, Saksena A, Vorstenbosch J, Finnson KW, Buschmann MD, Philip A.
|
| Biochim Biophys Acta 1813(5):742-53. doi: 10.1016/j.bbamcr.2011.01.028. Epub 2011 Feb 2.
2011
|
| 41 | CAV1, PTRF
|
| Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1.
|
| Bai L, Deng X, Li J, Wang M, Li Q, An W, A D, Cong YS.
|
| Cell Res 21(7):1088-101. doi: 10.1038/cr.2011.56. Epub 2011 Mar 29.
2011
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| 42 | CAV1
|
| Caveolin-1 protects against sepsis by modulating inflammatory response, alleviating bacterial burden, and suppressing thymocyte apoptosis.
|
| Feng H, Guo L, Song Z, Gao H, Wang D, Fu W, Han J, Li Z, Huang B, Li XA.
|
| J Biol Chem 285(33):25154-60. Epub 2010 Jun 9.
2010
|
| 43 | CAV1, CAV2
|
| Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.
|
| Thorleifsson G, Walters GB, Hewitt AW, Masson G, Helgason A, DeWan A, Sigurdsson A, Jonasdottir A, Gudjonsson SA, Magnusson KP, Stefansson H, Lam DS, Tam PO, Gudmundsdottir GJ, Southgate L, Burdon KP, Gottfredsdottir MS, Aldred MA, Mitchell P, St Clair D, Collier DA, Tang N, Sveinsson O, Macgregor S, Martin NG, Cree AJ, Gibson J, Macleod A, Jacob A, Ennis S, Young TL, Chan JC, Karwatowski WS, Hammond CJ, Thordarson K, Zhang M, Wadelius C, Lotery AJ, Trembath RC, Pang CP, Hoh J, Craig JE, Kong A, Mackey DA, Jonasson F, Thorsteinsdottir U, Stefansson K.
|
| Nat Genet 42(10):906-9. Epub 2010 Sep 12.
2010
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| 44 | CAV1
|
| Caveolin-1 activates Rab5 and enhances endocytosis through direct interaction.
|
| Hagiwara M, Shirai Y, Nomura R, Sasaki M, Kobayashi K, Tadokoro T, Yamamoto Y.
|
| Biochem Biophys Res Commun 378(1):73-8. Epub 2008 Nov 12.
2009
|
| 45 | CAV1, PRKCDBP, PTRF, SDPR
|
| SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function.
|
| McMahon KA, Zajicek H, Li WP, Peyton MJ, Minna JD, Hernandez VJ, Luby-Phelps K, Anderson RG.
|
| EMBO J 28(8):1001-15. Epub 2009 Mar 5. 2009
|
| 46 | CAV1, HEPACAM
|
| Interaction of the immunoglobulin-like cell adhesion molecule hepaCAM with caveolin-1.
|
| Moh MC, Lee LH, Zhang T, Shen S.
|
| Biochem Biophys Res Commun 378(4):755-60. Epub 2008 Dec 6.
2009
|
| 47 | CAV1
|
| The absence of caveolin-1 increases proliferation and anchorage- independent growth by a Rac-dependent, Erk-independent mechanism.
|
| Cerezo A, Guadamillas MC, Goetz JG, Sánchez-Perales S, Klein E, Assoian RK, del Pozo MA.
|
| Mol Cell Biol 29(18):5046-59. Epub 2009 Jul 20.
2009
|
| 48 | CAV1, CAV2, CAV3
|
| Caveolins sequester fatty acids on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation and protect cells from lipotoxicity.
|
| Simard JR, Meshulam T, Pillai BK, Kirber MT, Brunaldi K, Xu S, Pilch PF, Hamilton JA.
|
| J Lipid Res Lipid Res. 2009 Jul 15. [Epub ahead of print]PMID: 19605920 2009
|
| 49 | CAV1
|
| Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration.
|
| Zhao YY, Zhao YD, Mirza MK, Huang JH, Potula HH, Vogel SM, Brovkovych V, Yuan JX, Wharton J, Malik AB.
|
| J Clin Invest. 119(7):2009-18. 2009
|
| 50 | CAV1, IFITM1
|
| Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation.
|
| Xu Y, Yang G, Hu G.
|
| Acta Biochim Biophys Sin (Shanghai) 41(6):488-94.
2009
|
| 51 | CAV1, ITPR3, TRPC1
|
| Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells.
|
| Sundivakkam PC, Kwiatek AM, Sharma TT, Minshall RD, Malik AB, Tiruppathi C.
|
| Am J Physiol Cell Physiol 296(3):C403-13. doi: 10.1152/ajpcell.00470.2008. Epub 2008 Dec 3.
2009
|
| 52 | KCNMA1, CAV1
|
| Slo1 caveolin-binding motif, a mechanism of caveolin-1-Slo1 interaction regulating Slo1 surface expression.
|
| Alioua A, Lu R, Kumar Y, Eghbali M, Kundu P, Toro L, Stefani E.
|
| J Biol Chem 283(8):4808-17. Epub 2007 Dec 12. 2008
|
| 53 | BSCL3, CAV1
|
| Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy.
|
| Kim CA, Delépine M, Boutet E, El Mourabit H, Le Lay S, Meier M, Nemani M, Bridel E, Leite CC, Bertola DR, Semple RK, O'Rahilly S, Dugail I, Capeau J, Lathrop M, Magré J.
|
| J Clin Endocrinol Metab 93(4):1129-34. Epub 2008 Jan 22.
2008
|
| 54 | AGPAT2, BSCL1, BSCL2, BSCL3, CAV1
|
| Novel subtype of congenital generalized lipodystrophy associated with muscular weakness and cervical spine instability.
|
| Simha V, Agarwal AK, Aronin PA, Iannaccone ST, Garg A.
|
| Am J Med Genet A 146A(18):2318-26.
2008
|
| 55 | BMPR2, CAV1
|
| Caveolin-1 regulates BMPRII localization and signaling in vascular smooth muscle cells.
|
| Wertz JW, Bauer PM.
|
| Biochem Biophys Res Commun 375(4):557-61. Epub 2008 Aug 24.PMID: 18725205 2008
|
| 56 | CAV1, FLNA
|
| Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration.
|
| Ravid D, Chuderland D, Landsman L, Lavie Y, Reich R, Liscovitch M.
|
| Exp Cell Res 314(15):2762-73. Epub 2008 Jun 12.
2008
|
| 57 | EMP2, CAV1
|
| The Tetraspan Protein EMP2 Regulates Expression of Caveolin-1.
|
| Forbes A, Wadehra M, Mareninov S, Morales S, Shimazaki K, Gordon LK, Braun J.
|
| J Biol Chem 282(36):26542-51. Epub 2007 Jul 3. 2007
|
| 58 | CAV1, SLC1A1
|
| Caveolin-1 regulates the delivery and endocytosis of the glutamate transporter, excitatory amino acid carrier 1.
|
| Gonz‡lez MI, Krizman-Genda E, Robinson MB.
|
| J Biol Chem 282(41):29855-65. Epub 2007 Aug 22. 2007
|
| 59 | CAV1, SCP2
|
| A new N-terminal recognition domain in caveolin-1 interacts with sterol carrier protein-2 (SCP-2).
|
| Parr RD, Martin GG, Hostetler HA, Schroeder ME, Mir KD, Kier AB, Ball JM, Schroeder F.
|
| Biochemistry 46(28):8301-14. Epub 2007 Jun 20.
2007
|
| 60 | DYSF, CAV1, CAV3
|
| Aberrant dysferlin trafficking in cells lacking caveolin or expressing dystrophy mutants of caveolin-3.
|
| Hernandez-Deviez DJ, Martin S, Laval SH, Lo HP, Cooper ST, North KN, Bushby K, Parton RG.
|
| Hum Mol Genet 15(1):129-42. Epub 2005 Nov 30. 2006
|
| 61 | CAV1
|
| Caveolin-1 is essential for liver regeneration.
|
| Fernandez MA, Albor C, Ingelmo-Torres M, Nixon SJ, Ferguson C, Kurzchalia T, Tebar F, Enrich C, Parton RG, Pol A.
|
| Science 313(5793):1628-32. 2006
|
| 62 | BRCA1,CAV1
|
| Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells.
|
| Glait C, Ravid D, Lee SW, Liscovitch M, Werner H.
|
| FEBS Lett 580(22):5268-74. Epub 2006 Sep 11. 2006
|
| 63 | PTPN1, CAV1
|
| Identification of phosphocaveolin-1 as a novel protein tyrosine phosphatase 1B substrate.
|
| Lee H, Xie L, Luo Y, Lee SY, Lawrence DS, Wang XB, Sotgia F, Lisanti MP, Zhang ZY.
|
| Biochemistry 45(1):234-40. 2006
|
| 64 | EPHB1, CAV1
|
| Caveolin-1 is required for signaling and membrane targeting of EphB1 receptor tyrosine kinase.
|
| Vihanto MM, Vindis C, Djonov V, Cerretti DP, Huynh-Do U.
|
| J Cell Sci 119(Pt 11):2299-309. 2006
|
| 65 | SPRY1, SPRY2, SPRY3, SPRY4, CAV1
|
| A functional interaction between sprouty proteins and caveolin-1.
|
| Cabrita MA, JŠggi F, Widjaja SP, Christofori G.
|
| J Biol Chem 281(39):29201-12. Epub 2006 Jul 28. 2006
|
| 66 | CAV1
|
| Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels.
|
| Yu J, Bergaya S, Murata T, Alp IF, Bauer MP, Lin MI, Drab M, Kurzchalia TV, Stan RV, Sessa WC.
|
| J Clin Invest. 116(5):1284-91. 2006
|
| 67 | SPRED1, CAV1
|
| The Sprouty-related protein, Spred-1, localizes in a lipid raft/caveola and inhibits ERK activation in collaboration with caveolin-1.
|
| Nonami A, Taketomi T, Kimura A, Saeki K, Takaki H, Sanada T, Taniguchi K, Harada M, Kato R, Yoshimura A.
|
| Genes Cells 10(9):887-95. 2005
|
| 68 | CAV1
|
| The subcellular localization control of integrin linked kinase 1 through its protein-protein interaction with caveolin-1.
|
| Chun J, Hyun S, Kwon T, Lee EJ, Hong SK, Kang SS.
|
| Cell Signal. 17(6):751-60. 2005
|
| 69 | CAV1
|
| Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide.
|
| Kim HP, Wang X, Nakao A, Kim SI, Murase N, Choi ME, Ryter SW, Choi AM.
|
| Proc Natl Acad Sci U S A. 102(32):11319-24. 2005
|
| 70 | CAV1,HTR1F,HTR2A
|
| Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors.
|
| Bhatnagar A, Sheffler DJ, Kroeze WK, Compton-Toth B, Roth BL.
|
| J Biol Chem 279(33):34614-23. Epub 2004 Jun 9. 2004
|
| 71 | CAV1
|
| Links between CD147 function, glycosylation, and caveolin-1.
|
| Tang W, Chang SB, Hemler ME.
|
| Mol Biol Cell. 15(9):4043-50. 2004
|
| 72 | CAV1, CAV2, FRA7G, TES
|
| Candidate tumor suppressor genes at FRA7G are coamplified with MET and do not suppress malignancy in a gastric cancer
|
| Han SY, Druck T, Huebner K.
|
| Genomics 81(2):105-7. 2003
|
| 73 | CAV1
|
| Mutational, epigenetic and expressional analyses of caveolin-1 gene in cervical cancers.
|
| Chan TF, Su TH, Yeh KT, Chang JY, Lin TH, Chen JC, Yuang SS, Chang JG.
|
| Int J Oncol 23(3):599-604. 2003
|
| 74 | CAV1
|
| Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A.
|
| Li L, Ren CH, Tahir SA, Ren C, Thompson TC.
|
| Mol Cell Biol. 23(24):9389-404. 2003
|
| 75 | CAV1, CD44, CDH1, LPL, PMEPA1
|
| Cytogenetics and molecular genetics of cancer of the prostate.
|
| Brothman AR.
|
| Am J Med Genet 115(3):150-6. 2002
|
| 76 | CAV1
|
| Some protein tyrosine phosphatases target in part to lipid rafts and interact with caveolin-1.
|
| Caselli A, Mazzinghi B, Camici G, Manao G, Ramponi G.
|
| Biochem Biophys Res Commun. 296(3):692-7. 2002
|
| 77 | CAV1
|
| Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx.
|
| Vargas L, Nore BF, Berglof A, Heinonen JE, Mattsson PT, Smith CI, Mohamed AJ.
|
| J Biol Chem. 277(11):9351-7. 2002
|
| 78 | CAV1
|
| A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase.
|
| Cao H, Courchesne WE, Mastick CC.
|
| J Biol Chem. 277(11):8771-4. 2002
|
| 79 | CAV1
|
| Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice.
|
| Zhao YY, Liu Y, Stan RV, Fan L, Gu Y, Dalton N, Chu PH, Peterson K, Ross J Jr, Chien KR.
|
| Proc Natl Acad Sci U S A. 99(17):11375-80. 2002
|
| 80 | CAV1
|
| Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1.
|
| Lee H, Park DS, Wang XB, Scherer PE, Schwartz PE, Lisanti MP.
|
| J Biol Chem. 277(37):34556-67. 2002
|
| 81 | CAV1
|
| Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice.
|
| Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, Kurzchalia TV.
|
| Science 293(5539):2449-52. 2001
|
| 82 | CAV1
|
| Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer.
|
| Tahir SA, Yang G, Ebara S, Timme TL, Satoh T, Li L, Goltsov A, Ittmann M, Morrisett JD, Thompson TC.
|
| Cancer Res 61(10):3882-5. 2001
|
| 83 | CAV1, MALL
|
| BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells.
|
| de Marco MC, Kremer L, Albar JP, Martinez-Menarguez JA, Ballesta J, Garcia-Lopez MA, Marazuela M, Puertollano R, Alonso MA.
|
| J Biol Chem 276(25):23009-17. 2001
|
| 84 | CAV1
|
| Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene.
|
| Wiechen K, Diatchenko L, Agoulnik A, Scharff KM, Schober H, Arlt K, Zhumabayeva B, Siebert PD, Dietel M, Schafer R, Sers C.
|
| Am J Pathol 159(5):1635-43. 2001
|
| 85 | CAV1
|
| Caveolin-1 interacts with androgen receptor. A positive modulator of androgen receptor mediated transactivation.
|
| Lu ML, Schneider MC, Zheng Y, Zhang X, Richie JP.
|
| J Biol Chem. 276(16):13442-51. 2001
|
| 86 | CAV1
|
| Two distinct caveolin-1 domains mediate the functional interaction of caveolin-1 with protein kinase A.
|
| Razani B, Lisanti MP.
|
| Am J Physiol Cell Physiol. 281(4):C1241-50. 2001
|
| 87 | CAV1
|
| Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
|
| Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H Jr, Kneitz B, Lagaud G, Christ GJ, Edelmann W, Lisanti MP.
|
| J Biol Chem. 276(41):38121-38. 2001
|
| 88 | CAV1, CAV2
|
| Genomic organization and transcriptional analysis of the human genes coding for caveolin-1 and caveolin-2.
|
| Fra AM, Pasqualetto E, Mancini M, Sitia R.
|
| Gene 243(1-2):75-83. 2000
|
| 89 | CAV1, PLD2
|
| Phospholipase D2: functional interaction with caveolin in low-density membrane microdomains.
|
| Czarny M, Fiucci G, Lavie Y, Banno Y, Nozawa Y, Liscovitch M.
|
| FEBS Lett. 467(2-3):326-32. 2000
|
| 90 | CAV1, CAV2
|
| Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors.
|
| Fra AM, et al.
|
| Genomics 56(3):355-6. No abstract available 1999
|
| 91 | CAV1
|
| Reduction of caveolin 1 gene expression in lung carcinoma cell lines.
|
| Racine C, et al.
|
| Biochem Biophys Res Commun 255(3):580-6. 1999
|
| 92 | CAV1
|
| Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines.
|
| Hurlstone AF, et al.
|
| Oncogene 18(10):1881-90. 1999
|
| 93 | CAV1, CAV2, D7S522
|
| Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines.
|
| Engelman JA, et al.
|
| FEBS Lett 448(2-3):221-30. 1999
|
| 94 | CAV1
|
| Regulation of G protein-coupled receptor kinases by caveolin.
|
| Carman CV, Lisanti MP, Benovic JL.
|
| J Biol Chem. 274(13):8858-64. 1999
|
| 95 | CAV1, CAV2
|
| Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe.
|
| Volonte D, Galbiati F, Li S, Nishiyama K, Okamoto T, Lisanti MP.
|
| J Biol Chem. 274(18):12702-9. 1999
|
| 96 | CAV1, CAV2, CAV3
|
| Affinity-purification and characterization of caveolins from the brain : differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types.
|
| Ikezu T, Ueda H, Trapp BD, Nishiyama K, Sha JF, Volonte D, Galbiati F, Byrd AL, Bassell G, Serizawa H, Lane WS, Lisanti MP, Okamoto T.
|
| Brain Res 804 : 177-192. 1998
|
| 97 | CAV1, CAV2, CAV3
|
| Molecular genetics of the caveolin gene family : implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy.
|
| Engelman JA, et al.
|
| Am J Hum Genet 63 : 1578-1587. 1998
|
| 98 | CAV1, CAV2, D7S522, FRA7G, ST7
|
| Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers.
|
| Engelman JA, et al.
|
| FEBS Lett 436 : 403-410. 1998
|
| 99 | CAV1
|
| Expression of caveolin-1 in human T cell leukemia cell lines.
|
| Hatanaka M, et al.
|
| Biochem Biophys Res Commun 253(2):382-7. 1998
|
| 100 | CAV1
|
| A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth.
|
| Wary KK, Mariotti A, Zurzolo C, Giancotti FG.
|
| Cell 94(5):625-34. 1998
|
| 101 | CAV1
|
| Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein.
|
| Ikezu T, Trapp BD, Song KS, Schlegel A, Lisanti MP, Okamoto T.
|
| J Biol Chem. 273(17):10485-95. 1998
|
| 102 | CAV1, CAV2
|
| Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo.
|
| Scherer PE, Lewis RY, Volonte D, Engelman JA, Galbiati F, Couet J, Kohtz DS, van Donselaar E, Peters P, Lisanti MP.
|
| J Biol Chem. 272(46):29337-46. 1997
|
| 103 | CAV1, CAV2
|
| Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.
|
| Scherer PE, Okamoto T, Chun M, Nishimoto I, Lodish HF, Lisanti MP.
|
| Proc Natl Acad Sci U S A. 93(1):131-5. 1996
|
| 104 | CAV1
|
| Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe.
|
| Scherer PE, Tang Z, Chun M, Sargiacomo M, Lodish HF, Lisanti MP.
|
| J Biol Chem 270(27):16395-401. 1995
|