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FLASH GENE
Symbol NCAN contributors: /np - updated : 03-02-2004
HGNC name neurocan
HGNC id 2465
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • lectin C-type domain/ SUSHI domain
  • zn immunoglobulin-like domain and repeating motifs characteristic of hyaluronic acid-binding region of proteoglycans
    • HOMOLOGY
    interspecies homolog to murine Cspg3
    intraspecies homolog to AGC1,homolog
    Homologene
    FAMILY
  • aggrecan/versican proteoglycan family
    • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • chondroitin sulfate proteoglycan, involved in the modulation of cell adhesion and migration (axon guidance and neurite growth)
    • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS