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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

TNFSF12

contributors: mct/npt/pgu - updated : 05-11-2015

HGNC name	tumor necrosis factor (ligand) superfamily, member 12
HGNC id	11927

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in hepatocellular carcinoma constitutional     --over   differentially upregulated in patients with idiopathic dilated cardiomyopathy compared with other forms of heart disease and normal control subjects

Susceptibility

Variant & Polymorphism

Candidate gene	candidate clinical biomarker for lupus nephritis
Marker
Therapy target
	System Type Disorder Pubmed miscelleaneous urinary   might be a target for therapeutic intervention in renal and vascular injury cancer reproductive ovary targeted therapy against TWEAK-TWEAKR signaling system as an adjuvant to surgery may improve clinical management of invasive ovarian cancer cells and advance the outcome of this devastating cancer

ANIMAL & CELL MODELS