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FLASH GENE

Symbol

OLR1

contributors: mct - updated : 14-04-2015

HGNC name	oxidized low density lipoprotein (lectin-like) receptor 1
HGNC id	8133

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	LOX-1 KO mice have low levels of the immunoglobulins in the heart (vs. the WT mice) and the expression of these immunoglobulins in the LOX-1 KO mice is upregulated several-fold when the mice are infused with Angiotensin II
	its deletion (Lox-1 knockout, KO) reduces atherosclerosis in LDLr KO mice fed a high cholesterol diet