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FLASH GENE

Symbol

DFFB

contributors: mct/npt - updated : 25-02-2020

HGNC name	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
HGNC id	2773

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   low expression levels of DFFB and the absence of DNA laddering as common molecular traits in Glioblastoma (GBM)

Susceptibility

Variant & Polymorphism

Candidate gene	unlikely to be a candidate neuroblastoma tumor suppressor gene
Marker
Therapy target

ANIMAL & CELL MODELS