| 1 | DFFB, DNASE1, DNASE1L3
|
| The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB.
|
| Han DSC, Ni M, Chan RWY, Chan VWH, Lui KO, Chiu RWK, Lo YMD.
|
| Am J Hum Genet 106(2):202-214. doi: 10.1016/j.ajhg.2020.01.008. Epub 2020 Jan 30.
2020
|
| 2 | DFFB
|
| An intrinsic DFF40/CAD endonuclease deficiency impairs oligonucleosomal DNA hydrolysis during caspase-dependent cell death: a common trait in human glioblastoma cells.
|
| Sánchez-Osuna M, Martínez-Escardó L, Granados-Colomina C, Martínez-Soler F, Pascual-Guiral S, Iglesias-Guimarais V, Velasco R, Plans G, Vidal N, Tortosa A, Barcia C, Bruna J, Yuste VJ.
|
| Neuro Oncol 18(7):950-61. doi: 10.1093/neuonc/nov315. Epub 2016 Jan 10.
2016
|
| 3 | DFFB, DNASE1L3
|
| Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonuclease that translocates to the nucleus during apoptosis.
|
| Errami Y, Naura AS, Kim H, Ju J, Suzuki Y, El-Bahrawy AH, Ghonim MA, Hemeida RA, Mansy MS, Zhang J, Xu M, Smulson ME, Brim H, Boulares AH.
|
| J Biol Chem 288(5):3460-8. doi: 10.1074/jbc.M112.423061. Epub 2012 Dec 10.
2013
|
| 4 | DFFB
|
| Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease.
|
| Iglesias-Guimarais V, Gil-Guiñon E, Gabernet G, García-Belinchón M, Sánchez-Osuna M, Casanelles E, Comella JX, Yuste VJ.
|
| J Biol Chem 287(10):7766-79. Epub 2012 Jan 17.
2012
|
| 5 | DFFB
|
| Early apoptotic reorganization of spliceosomal proteins involves caspases, CAD and rearrangement of NuMA.
|
| Dieker J, Iglesias-Guimarais V, Décossas M, Stevenin J, van der Vlag J, Yuste VJ, Muller S.
|
| Traffic 13(2):257-72. doi: 10.1111/j.1600-0854.2011.01307.x. Epub 2011 Nov 23.
2012
|
| 6 | DFFB
|
| Septic sera induces apoptosis and DNA fragmentation factor 40 activation in fibroblasts.
|
| Brabant D, Michael P, Bleiblo F, Saleh M, Narain R, Tai TC, Ramana CV, Parrillo JE, Kumar A, Kumar A.
|
| Biochem Biophys Res Commun 412(2):260-5. Epub 2011 Jul 28.
2011
|
| 7 | DFFB
|
| Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks.
|
| Larsen BD, Rampalli S, Burns LE, Brunette S, Dilworth FJ, Megeney LA.
|
| Proc Natl Acad Sci U S A 107(9):4230-5. Epub 2010 Feb 16.
2010
|
| 8 | DFFB
|
| The major apoptotic endonuclease DFF40/CAD is a deoxyribose-specific and double-strand-specific enzyme.
|
| Hanus J, Kalinowska-Herok M, Widlak P.
|
| Apoptosis 13(3):377-82.
2008
|
| 9 | DFFB, HMGB1
|
| High mobility group proteins stimulate DNA cleavage by apoptotic endonuclease DFF40/CAD due to HMG-box interactions with DNA.
|
| Kalinowska-Herok M, Wid³ak P.
|
| Acta Biochim Pol 55(1):21-6. Epub 2008 Feb 1.
2008
|
| 10 | DFFB, DNASE1L3
|
| Stage-specific expression of DNasegamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells.
|
| Shiokawa D, Shika Y, Araki S, Sunaga S, Mizuta R, Kitamura D, Tanuma S.
|
| Cell Death Differ 14(5):992-1000. Epub 2007 Jan 12.
2007
|
| 11 | DFFB
|
| The apoptotic endonuclease DFF40/CAD is inhibited by RNA, heparin and other polyanions.
|
| Widlak P, Garrard WT.
|
| Apoptosis 11(8):1331-7.
2006
|
| 12 | DFFA, DFFB
|
| Functional interaction of DFF35 and DFF45 with caspase-activated DNA fragmentation nuclease DFF40.
|
| Gu J, Dong RP, Zhang C, McLaughlin DF, Wu MX, Schlossman SF.
|
| J Biol Chem 274(30):20759-62. 1999
|
| 13 | DFFA, DFFB, XIAP
|
| A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.
|
| Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S.
|
| Nature 391(6662):43-50. Erratum in: Nature 1998 May 28;393(6683):396. 1998
|
| 14 | DFFB, DFFA
|
| CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45.
|
| Halenbeck R, et al.
|
| Curr Biol 8 : 537-540. 1998
|
| 15 | DFFB, DFFA
|
| Molecular cloning and characterization of human caspase-activated DNase.
|
| Mukae N, et al.
|
| Proc Natl Acad Sci U S A 95 : 9123-9128. 1998
|