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FLASH GENE

Symbol

DZIP3

contributors: mct - updated : 16-12-2014

HGNC name	DAZ interacting protein 3, zinc finger
HGNC id	30938

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	105.36 kb     33 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_014648 33 - 5568 NP_055463 138 1208 - 2003 12538761

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain         Reproductive female system ovary     highly   male system testis     highly Urinary kidney       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal   highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

intraspecies

homolog to PR repeat protein O

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm

basic FUNCTION

the combined presence of RNA binding and E3 activity in DZIP3 raises the possibility that both are mechanistically linked

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

HOTAIR associates with E3 ubiquitin ligases bearing RNA-binding domains, DZIP3 and MEX3B, as well as with their respective ubiquitination substrates, ATXN1 and SNUPN

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS