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FLASH GENE

Symbol

SFRP5

contributors: mct/npt - updated : 12-09-2016

HGNC name	secreted frizzled-related protein 5
HGNC id	10779

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	mice overexpressing Sfrp5 had fewer B-lymphocytes in the peripheral blood and spleen
	mice that lack functional Sfrp5 were resistant to diet-induced obesity
	Sfrp5-deficient mice fed a high-calorie diet developed severe glucose intolerance and hepatic steatosis, and their adipose tissue showed an accumulation of activated macrophages