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FLASH GENE

Symbol

F2RL3

contributors: mct - updated : 14-11-2015

HGNC name	coagulation factor II (thrombin) receptor-like 3
HGNC id	3540

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   during the progression of colon and prostate cancers tumoral     --low   occurs frequently in gastric cancers, may result from hypermethylation of the promoter and exhibits association with more aggressive gastric cancer

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

blood-brain barrier disruption and cerebral edema were also attenuated in PAR4-/- mice compared with wild-type animals