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FLASH GENE
Symbol ICAM4 contributors: npt/ - updated : 14-03-2007
HGNC name intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
HGNC id 5347
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal sequence an extracellular region
  • two Ig-like domains
  • a single transmembrane segment
  • a cytoplasmic C terminus
  • HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • ICAM family
  • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • adhesion molecule that binds to leukocyte adhesion LFA1 protein (integrin alpha-l/beta-2)
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) LW
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS