Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ICAM4 contributors: npt/ - updated : 14-03-2007
HGNC name intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
HGNC id 5347
DNA
TYPE functioning gene
STRUCTURE 1.55 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked Y status confirmed
Physical map
LOC162993 19p13.2 hypothetical protein LOC162993 UBE2L4 19q13.1-q13.2 ubiquitin-conjugating enzyme E2L 4 FBXL12 19p13.2 F-box and leucine-rich repeat protein 12 PIN1 19p13.2 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 UBL5 19p13.3 ubiquitin-like 5 LOC390888 19 similar to 60S ribosomal protein L10 (QM protein homolog) OLFM2 19p13.2 olfactomedin 2 COL5A3 19p13.2 collagen, type V, alpha 3 RDH8 19p13.2-p13.3 retinol dehydrogenase 8 (all-trans) LOC388502 19 similar to Complement C3 precursor LOC388503 19 similar to Complement C3-1 LOC147740 19p13.2 similar to complement C3 protein (GPC3) precursor FLJ11286 19p13.2 hypothetical protein FLJ11286 ANGPTL6 19p13.2 angiopoietin-like 6 PPAN 19p13 peter pan homolog (Drosophila) P2RY11 19p13.2 purinergic receptor P2Y, G-protein coupled, 11 EIF3S4 19p13.2 eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa DNMT1 19p13.2 DNA (cytosine-5-)-methyltransferase 1 EDG5 19p13.2 endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 LOC388504 19 LOC388504 MRPL4 19p13.2 mitochondrial ribosomal protein L4 ICAM1 19p13.3-p13.2 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor ICAM4 19p13.2-cen intercellular adhesion molecule 4, Landsteiner-Wiener blood group ICAM5 19p13.2 intercellular adhesion molecule 5, telencephalin LOC388505 MGC19604 19p13.2 similar to RIKEN cDNA B230118G17 gene RAVER1 19p13.2 RAVER1 ICAM3 19p13.3-p13.2 intercellular adhesion molecule 3 TYK2 19p13.2 tyrosine kinase 2 CDC37 19p13.2 CDC37 cell division cycle 37 homolog (S. cerevisiae) PDE4A 19p13.2 phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) KEAP1 19p13.2 kelch-like ECH-associated protein 1 EDG8 19p13.2 endothelial differentiation, sphingolipid G-protein-coupled receptor, 8 AUTL4 19p13.2 AUT-like 4, cysteine endopeptidase (S. cerevisiae) FLJ12949 19p13.2 hypothetical protein FLJ12949 CDKN2D 19p13.2 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) AP1M2 19p13.2 adaptor-related protein complex 1, mu 2 subunit CTL2 19p13.1 adaptor-related protein complex 1, mu 2 subunit ILF3 19p13 interleukin enhancer binding factor 3, 90kDa QTRT1 19p13.3 queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) DNM2 19p13.2 dynamin 2
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1420 23.7 237 - -
- - 1273 27 271 - -
- - 1196 27.4 272 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticerthrocyte
Lymphoid/Immunemacrophage
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal sequence an extracellular region
  • two Ig-like domains
  • a single transmembrane segment
  • a cytoplasmic C terminus
  • HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • ICAM family
  • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • adhesion molecule that binds to leukocyte adhesion LFA1 protein (integrin alpha-l/beta-2)
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) LW
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS