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FLASH GENE

Symbol

F2

contributors: SGE/npt - updated : 28-11-2007

HGNC name	coagulation factor II (thrombin)
HGNC id	3535

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

F2

Susceptibility

to ischemic heart disease (IHD)

Variant & Polymorphism other	G20210A heterozygosity alone and in combination with Factor V Leiden R506Q heterozygosity predicts 1.5 and 6.0 fold risk of IHD compared to non-carriers (Weischer 2009)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS