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FLASH GENE

Symbol

ETS1

contributors: mct - updated : 18-05-2015

HGNC name	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
HGNC id	3488

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	homozygous Ets1 deletion mice had large membranous ventricular septal defects, abnormal-appearing left ventricular morphology, characterized by a bifid cardiac apex, and non-apex-forming left ventricle
	Ets1-deficient mice develop a lupus-like disease characterized by high titers of immunoglobulin M (IgM) and IgG autoantibodies and immune-complex deposition in the kidneys