| 1 | ETS1
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| Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
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| Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Joo YB, Choi J, Bae SC, Boackle SA, Graham DC, Vyse TJ, Guthridge JM, Gaffney PM, Langefeld CD, Kelly JA, Greis KD, Kaufman KM, Harley JB, Kottyan LC.
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| Am J Hum Genet 96(5):731-9. doi: 10.1016/j.ajhg.2015.03.002. Epub 2015 Apr 9.
2015
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| 2 | ETS1
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| ETS1 Induces Human Trophoblast Differentiation.
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| Kessler CA, Stanek JW, Stringer KF, Handwerger S.
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| Endocrinology 156(5):1851-9. doi: 10.1210/en.2014-1760. Epub 2015 Feb 4.
2015
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| 3 | ETS1, SLFN11
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| SLFN11 Is a Transcriptional Target of EWS-FLI1 and a Determinant of Drug Response in Ewing Sarcoma.
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| Tang SW, Bilke S, Cao L, Murai J, Sousa FG, Yamade M, Rajapakse V, Varma S, Helman LJ, Khan J, Meltzer PS, Pommier Y.
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| Clin Cancer Res 21(18):4184-93. doi: 10.1158/1078-0432.CCR-14-2112.
2015
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| 4 | ETS1
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| ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells.
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| Plotnik JP, Budka JA, Ferris MW, Hollenhorst PC.
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| Nucleic Acids Res 42(19):11928-40. doi: 10.1093/nar/gku929. Epub 2014 Oct 7.
2014
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| 5 | ETS1, RFWD2
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| Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor.
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| Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, Lim E, Liu W, Bronson RT, Bowden M, Brock J, Krop IE, Dillon DA, Gygi SP, Mills GB, Richardson AL, Signoretti S, Yaffe MB, Kaelin WG Jr.
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| Cancer Cell 26(2):222-34. doi: 10.1016/j.ccr.2014.06.026.
2014
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| 6 | ETS1, RUNX1
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| Structural basis of Ets1 activation by Runx1.
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| Shrivastava T, Mino K, Babayeva ND, Baranovskaya OI, Rizzino A, Tahirov TH.
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| Leukemia 28(10):2040-8. doi: 10.1038/leu.2014.111. Epub 2014 Mar 20.
2014
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| 7 | ETS1, ETS2
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| Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation.
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| John S, Russell L, Chin SS, Luo W, Oshima R, Garrett-Sinha LA.
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| Mol Cell Biol 34(3):522-32. doi: 10.1128/MCB.00612-13. Epub 2013 Nov 25.
2014
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| 8 | CCL5, ETS1, FLI1
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| The Fli-1 transcription factor regulates the expression of CCL5/RANTES.
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| Lennard Richard ML, Sato S, Suzuki E, Williams S, Nowling TK, Zhang XK.
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| J Immunol 193(6):2661-8. doi: 10.4049/jimmunol.1302779. Epub 2014 Aug 6.
2014
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| 9 | ETS1, IL2, NFATC1, PRDM1
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| Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter.
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| Tsao HW, Tai TS, Tseng W, Chang HH, Grenningloh R, Miaw SC, Ho IC.
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| Proc Natl Acad Sci U S A 110(39):15776-81. doi: 10.1073/pnas.1304343110. Epub 2013 Sep 9. 2013
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| 10 | ETS1, FLI1
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| Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma.
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| Bonetti P, Testoni M, Scandurra M, Ponzoni M, Piva R, Mensah AA, Rinaldi A, Kwee I, Tibiletti MG, Iqbal J, Greiner TC, Chan WC, Gaidano G, Piris MA, Cavalli F, Zucca E, Inghirami G, Bertoni F.
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| Blood 122(13):2233-41. doi: 10.1182/blood-2013-01-475772. Epub 2013 Aug 7. Erratum in: Blood. 2014 May 8;123(19):3056.
2013
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| 11 | ETS1
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| Transcription factor Ets1 cooperates with estrogen receptor α to stimulate estradiol-dependent growth in breast cancer cells and tumors.
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| Kalet BT, Anglin SR, Handschy A, O'Donoghue LE, Halsey C, Chubb L, Korch C, Duval DL.
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| PLoS One 8(7):e68815. doi: 10.1371/journal.pone.0068815. Print 2013.
2013
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| 12 | ETS1, PARP1
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| The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.
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| Legrand AJ, Choul-Li S, Spriet C, Idziorek T, Vicogne D, Drobecq H, Dantzer F, Villeret V, Aumercier M.
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| PLoS One 8(2):e55883. doi: 10.1371/journal.pone.0055883. Epub 2013 Feb 6.
2013
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| 13 | ETS1
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| Modulation of Ets-1 expression in B lymphocytes is dependent on the antigen receptor-mediated activation signals and cell cycle status.
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| Raghunandan R, Frissora FW, Muthusamy N.
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| Scand J Immunol 77(2):75-83. doi: 10.1111/sji.12012.
2013
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| 14 | CTGF, ETS1
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| Ets-1 is essential for connective tissue growth factor (CTGF/CCN2) induction by TGF-β1 in osteoblasts.
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| Geisinger MT, Astaiza R, Butler T, Popoff SN, Planey SL, Arnott JA.
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| PLoS One 7(4):e35258. doi: 10.1371/journal.pone.0035258. Epub 2012 Apr 23.
2012
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| 15 | ATXN2, ETS1
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| ETS1 regulates the expression of ATXN2.
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| Scoles DR, Pflieger LT, Thai KK, Hansen ST, Dansithong W, Pulst SM.
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| Hum Mol Genet 21(23):5048-65. doi: 10.1093/hmg/dds349. Epub 2012 Aug 21.
2012
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| 16 | ATXN2, ETS1
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| ETS1 regulates the expression of ATXN2.
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| Scoles DR, Pflieger LT, Thai KK, Hansen ST, Dansithong W, Pulst SM.
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| Hum Mol Genet 21(23):5048-65. doi: 10.1093/hmg/dds349. Epub 2012 Aug 21.
2012
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| 17 | ETS1, RUNX1, TAL1
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| Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages.
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| Palii CG, Perez-Iratxeta C, Yao Z, Cao Y, Dai F, Davison J, Atkins H, Allan D, Dilworth FJ, Gentleman R, Tapscott SJ, Brand M.
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| EMBO J 30(3):494-509. Epub 2010 Dec 21.
2011
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| 18 | DAXX, ETS1
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| Characterizing the N- and C-terminal Small ubiquitin-like modifier (SUMO)-interacting motifs of the scaffold protein DAXX.
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| Escobar-Cabrera E, Okon M, Lau DK, Dart CF, Bonvin AM, McIntosh LP.
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| J Biol Chem 286(22):19816-29. Epub 2011 Mar 7.
2011
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| 19 | ELF1, ETS1, GABPA, PF4
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| Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site.
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| Okada Y, Nobori H, Shimizu M, Watanabe M, Yonekura M, Nakai T, Kamikawa Y, Wakimura A, Funahashi N, Naruse H, Watanabe A, Yamasaki D, Fukada S, Yasui K, Matsumoto K, Sato T, Kitajima K, Nakano T, Aird WC, Doi T.
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| PLoS One 6(9):e24837. doi: 10.1371/journal.pone.0024837. Epub 2011 Sep 12.
2011
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| 20 | DEL11QD, ETS1, HLHS2
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| Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice.
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| Ye M, Coldren C, Liang X, Mattina T, Goldmuntz E, Benson DW, Ivy D, Perryman MB, Garrett-Sinha LA, Grossfeld P.
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| Hum Mol Genet 19(4):648-56. Epub 2009 Nov 26.
2010
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| 21 | ELF1, ETS1, ETS2, FLI1
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| The mouse and human Fli1 genes are similarly regulated by Ets factors in T cells.
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| Svenson JL, Chike-Harris K, Amria MY, Nowling TK.
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| Genes Immun 11(2):161-72. Epub 2009 Oct 15.PMID: 19829305 2010
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| 22 | ETS1
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| Ets-1 p27: a novel Ets-1 isoform with dominant-negative effects on the transcriptional properties and the subcellular localization of Ets-1 p51.
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| Laitem C, Leprivier G, Choul-Li S, Begue A, Monte D, Larsimont D, Dumont P, Duterque-Coquillaud M, Aumercier M.
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| Oncogene 28(20):2087-99. Epub 2009 Apr 20.
2009
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| 23 | ETS1
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| Ets-1 regulates plasma cell differentiation by interfering with the activity of the transcription factor Blimp-1.
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| John SA, Clements JL, Russell LM, Garrett-Sinha LA.
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| J Biol Chem 283(2):951-62. Epub 2007 Oct 31. 2008
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| 24 | ERBB2, ETS1, MMP1
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| Ets-1 upregulates HER2-induced MMP-1 expression in breast cancer cells.
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| Park YH, Jung HH, Ahn JS, Im YH.
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| Biochem Biophys Res Commun 377(2):389-94. Epub 2008 Oct 11.
2008
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| 25 | EREG, ETS1
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| Epiregulin expression by Ets-1 and ERK signaling pathway in Ki-ras-transformed cells.
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| Cho MC, Choi HS, Lee S, Kim BY, Jung M, Park SN, Yoon DY.
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| Biochem Biophys Res Commun 377(3):832-7. doi: 10.1016/j.bbrc.2008.10.053. Epub 2008 Oct 21.
2008
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| 26 | ETS1, PIAS4
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| PIASy controls ubiquitination-dependent proteasomal degradation of Ets-1.
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| Nishida T, Terashima M, Fukami K, Yamada Y.
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| Biochem J 405(3):481-8.
2007
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| 27 | ETS1, MMP1, PLAU, SP100
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| SP100 inhibits ETS1 activity in primary endothelial cells.
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| Yordy JS, Moussa O, Pei H, Chaussabel D, Li R, Watson DK.
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| Oncogene 24(5):916-31.
2005
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| 28 | CHUK, TP53, ETS1
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| Identification and characterization of the IKKalpha promoter: positive and negative regulation by ETS-1 and p53, respectively.
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| Gu L, Zhu N, Findley HW, Woods WG, Zhou M.
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| J Biol Chem 279(50):52141-9. Epub 2004 Oct 5. 2004
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| 29 | ETS1, SP100
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| SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion.
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| Yordy JS, Li R, Sementchenko VI, Pei H, Muise-Helmericks RC, Watson DK.
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| Oncogene 23(39):6654-65.
2004
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| 30 | ETS1, EWSR1, TNC
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| Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
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| Watanabe G, Nishimori H, Irifune H, Sasaki Y, Ishida S, Zembutsu H, Tanaka T, Kawaguchi S, Wada T, Hata J, Kusakabe M, Yoshida K, Nakamura Y, Tokino T.
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| Genes Chromosomes Cancer 36(3):224-32. 2003
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| 31 | ETS1, ETS2, TDP2
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| EAPII interacts with ETS1 and modulates its transcriptional function.
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| Pei H, Yordy JS, Leng Q, Zhao Q, Watson DK, Li R.
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| Oncogene 22(18):2699-709. 2003
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| 32 | CDKN2A, ETS1, ETS2, ID1
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| Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence.
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| Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, Ohashi Y, Sharrocks AD, Peters G, Hara E.
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| Nature 409(6823):1067-70. 2001
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| 33 | ETS1, SLEB11Q
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| 3' polymorphisms of ETS1 are associated with different clinical phenotypes in SLE.
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| Sullivan KE, Piliero LM, Dharia T, Goldman D, Petri MA.
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| Hum Mutat 16(1):49-53. 2000
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| 34 | DAXX, ETS1
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| EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes.
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| Li R, Pei H, Watson DK, Papas TS.
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| Oncogene 19(6):745-53. 2000
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| 35 | ETS1, PAX2, PAX3, PAX5
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| The highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes.
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| Wheat W, Fitzsimmons D, Lennox H, Krautkramer SR, Gentile LN, McIntosh LP, Hagman J.
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| Mol Cell Biol 19(3):2231-41. 1999
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| 36 | RUNX2, ETS1, SPP1
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| Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues.
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| Sato M, et al.
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| Oncogene 17 : 1517-1525. 1998
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| 37 | ETS1
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| Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene.
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| Bories JC, Willerford DM, Grevin D, Davidson L, Camus A, Martin P, Stehelin D, Alt FW.
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| Nature 377(6550):635-8. 1995
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| 38 | ETS1
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| Transposition of the oncogene ets-1 in t(11;19) translocation in acute leukemia.
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| Wang N, et al.
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| Cancer Genet Cytogenet 50 : 199-205. 1990
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| 39 | ETS1
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| The ETS-domain : a new DNA-binding motif that recognizes a purine-rich core DNA sequence.
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| Karim FD, et al.
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| Genes Dev 4 : 1451-1453. 1990
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| 40 | PGR, D11S29, ETS1, NCAM1, HMBS
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| Fine mapping of the long arm of human chromosome 11 by in situ hybridization, using different translocations, including the t(11;22) of Ewing sarcoma.
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| BŽrubŽ D, et al.
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| Cytogenet Cell Genet 54 : 142-147. 1990
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| 41 | ETS1, ETS2
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| The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation.
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| Wasylyk B, et al.
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| Nature 346 : 191-193. 1990
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| 42 | ETS1
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| Taq I RFLP linked to the human ets-1 gene.
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| Aparicio JMR, et al.
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| Nucleic Acids Res 17 : 4913. 1989
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| 43 | ETS1
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| The oncogene ETS1 is distant from the chromosome 11 breakpoint in leukaemic cells with the t(11;19)(q23;p13).
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| Kennedy MA, et al.
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| Leuk Res 13 : 459-463. 1989
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| 44 | NCAM1, ETS1, D11S29
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| Precise in situ localization of NCAM, ETS1, and D11S29 on human meiotic chromosomes.
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| Bello MJ, et al.
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| Cytogenet Cell Genet 52 : 7-10. 1989
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| 45 | ETS1, ETS2, D1S100, D1S101
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| Detection of single-copy genes by nonisotopic in situ hybridization on human chromosomes.
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| Cherif D, et al.
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| Hum Genet 81 : 358-362. 1989
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| 46 | CD3D, CD3E, ETS1, NCAM1, THY1
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| Mapping studies and expression of genes located on human chromosome 11, band q23.
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| Savage PD, Jones C, Silver J, Geurts van Kessel AH, Gonzalez-Sarmiento R, Palm L, Hanson CA, Kersey JH.
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| Cytogenet Cell Genet 49 : 289-292. 1988
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| 47 | ETS1
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| Further localization of ETS1 indicates that the chromosomal rearrangement in Ewing sarcoma does not occur at fra(11)(q23).
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| Simmers RN, et al.
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| Hum Genet 78 : 144-147. 1988
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| 48 | ETS1
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| Sst I RFLP linked to the human ets-1 gene.
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| Kerckaert JP, et al.
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| Nucleic Acids Res 15 : 5905. 1987
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| 49 | ETS1, ETS2
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| Hu-ets-1 and Hu-ets-2 genes are transposed in acute leukemias with (4;11) and (8;21) translocations.
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| Sacchi N, et al.
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| Science 231 : 379-381. 1986
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| 50 | ETS1
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| Amplification and rearrangement of Hu-ets-1 in leukemia and lymphoma with involvement of 11q23.
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| Rovigatti U, et al.
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| Science 232 : 398-400. 1986
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| 51 | ETS1
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| Conserved chromosomal positions of dual domains of the ets protooncogene in cats, mice, and humans.
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| Watson DK, McWilliams-Smith MJ, Kozak C, Reeves R, Gearhart J, Nunn MF, Nash W, Fowle JR 3rd, Duesberg P, Papas TS, et al.
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| Proc Natl Acad Sci U S A 83 : 1792-1796. 1986
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| 52 | ETS1
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| A polymorphic SstI site within the human ets-1 gene in the 11q23 region.
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| Sacchi N, et al.
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| Nucleic Acids Res 14 : 9545. 1986
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| 53 | ETS1, IFN1@, IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA16, IFNA17, IFNA21, IFNAP22, IFNB1
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| Interferon and c-ets-1 genes in the translocation (9:11)(p22:q23) in human acute monocytic leukemia.
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| Diaz MO, et al.
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| Science 231 : 265-267. 1986
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| 54 | ETS1, ETS2
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| The ets sequence from the transforming gene of avian erythroblastosis virus, E26, has unique domains on human chromosomes 11 and 21 : both loci are transcriptionally active.
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| Watson DK, McWilliams-Smith MJ, Nunn MF, Duesberg PH, O'Brien SJ, Papas TS.
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| Proc Natl Acad Sci U S A 82 : 7294-7298. 1985
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| 55 | ETS1
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| Chromosomal localization of the human proto-oncogene c-ets.
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| Taisne C de, et al.
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| Nature 310 : 581-583. 1984
|