protein
| PAX2, PAX3, PAX5 (amino subterminal domain) potentially important for cellular differentiation |
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coregulating osteopontin with PEBP2 alpha |
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cooperating with cFos and cJUN SP100 for transcriptional activation |
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activating CDKN2A |
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binding to DAXX |
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interacting with UBE2I |
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SP100 interacts with the ETS1 transcription factor, reduces ETS1-DNA binding and inhibits ETS1 transcriptional activity on the MMP1 and PLAU promoters |
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interacting with ERBB2 and MMP1 (enhancing the ERBB2-induced expression of MMP1) |
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TAL1 interacts with RUNX1 and ETS1, and these transcription factors are critically required for TAL1 binding to genes that modulate T-cell differentiation |
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interaction of a C-terminal fragment of DAXX with an N-terminal fragment of the sumoylated ETS1 transcription factor mediated by SIM-C |
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ETS1 is essential for connective tissue growth factor (CTGF/CCN2) induction by TGFB1 in osteoblasts |
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ETS1 activates, by direct interaction, the catalytic activity of PARP1 and is then poly(ADP-ribosyl)ated in a DNA-independent manner |
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cooperates with ESR1 to stimulate estradiol-dependent growth in breast cancer cells and tumors |
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promotes the expression of IL2 by nuclear factor of activated T-cells (NFAT)-dependent mechanisms |
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very likely directly suppresses the expression of PRDM1 in Th1 cells by binding to the EBS2 of the PRDM1 promoter |
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critical role of direct ETS1•RUNX1 interaction in ETS1 activation |
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ETS1, another Ets family member, and FLI1 drive transcription from the CCL5 promoter, although FLI1 transactivation was significantly stronger |
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ETS1 phosphorylation of a neighboring tyrosine residue by Src family kinases disrupts RFWD2 binding, thereby stabilizing ETS1 |
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ETS1 acts as a positive regulator for SLFN11 expression in breast cancer cells |