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FLASH GENE

Symbol

CAPN1

contributors: mct/pgu - updated : 06-06-2016

HGNC name	calpain 1, (mu/I) large subunit
HGNC id	1476

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Capn1 knock-out mice may serve as a useful model system for neuronal protection and apoptosis in traumatic brain injury and other neurodegenerative disorders in which oxidative stress plays a role
	Calpain-1 protein and activity in mitochondria were elevated in diabetic mouse hearts